아토피 선별진단을 위한 PhadiatopⓇ 검사의 유용성 평가: 한국인 기관지천식 환자에서 CAPⓇ 특이 IgE 성적을 기준으로

Abstract

Background :Phadiatop test which was developed for screening of atopy in eastern asia area, has not been sufficiently evaluated In Korea In our previous study, the clinical usefulness of Phadiatop test for screening of atopy was evaluated on atopics and non-atopics defined by the results of skin prick tests with 10 inhalant allergens in Korea In this study, we evaluated the usefulness of Phadiatop test for screening of atopy based on the level of CAP specrfic IgE In Korean asthmatics Method :On 136 Korean asthmatics, the level of CAP specific IgE to 10 important inhalant allergens and the level of Phadiatop specrfic IgE to mixture of 8 Important inhalant allergens in Korea were measured Atopics and non-atopics were defined by the results of CAP specific IgE and the sensitivity, specificity, predictive value of a positive and negative result, and concordance rate of Phadiatop test were estimated Result :The sensitivity, specificity, predictive values of a positive and negative result, and concordance rate of Phadiatop test were 90 5%, 95 O%, 99 I%, 63 3%, and 91 2%, respectively Conclusion :Phadiatop test was very sensitive, raped and convenient, and corresponded well to the results of CAP specific IgE We concluded that Phadiatop test IS very useful as a screening tool of atopy In Korea