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혈청 고밀도 지단백 직접 측정법의 평가
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김정호 | - |
dc.date.accessioned | 2020-07-02T17:42:46Z | - |
dc.date.available | 2020-07-02T17:42:46Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 1015-6445 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176998 | - |
dc.description.abstract | Background :Serum high density llpoproteln (HDL)-cholesterol level IS used as an assessment of the risk of coronary heart disease. In this study, we evaluated direct measurement of HDL-cholesterol in serum with polyethylene-modlfled enzymes and sulfated a-cyclodextrin Method :We evaluated the precision, the lower limit of detection, the recovery rate, the linearity, the Interference for hemoglobin and the comparlslon with the result of HDL-cholesterol measured by selective preclpltatlon method We also studied the specificity of this direct method for very low density llpoproteln (VLDL) and low density lipoprotein (LDL) Result :The total ImprecIsIon was 3 8% (low), 3 5% (mlddle), 3 2% (high) The lower limit of detectjon was 0 mg/L The recovery rate was satisfactory The linearlty was also (r`=O 99) This method showed a good correlation (r`=O 97) with the selective preclpltatlon method in HDL-cholesterol measurement VLDL-cholesterol (up to 300 mg/L) Increased HDL-cholesterol only less than 3% but Increased VLDL-cholesterol to 400 mg/L, more than 750 mg/L caused 5% and 15% of overestlmatlon of HDL-cholesterol, respectively LDL-cholesterol (142-l ,073 mg/L) Increased or decreased HDL-cholesterol by some degree (about 15%). Hemoglobin (up to 3,000mg/L) did not influence this assay Conclusion :The drrect measurement of HDL-cholesterol IS satisfactory method in HDL-cholesterol measurement In good analytlcal performance and may be anticipated to reduce workload of laboratory because the sample pretreatment IS not necessary | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한임상병리학회 | - |
dc.relation.isPartOf | Korean Journal of Clinical Pathology (대한임상병리학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 혈청 고밀도 지단백 직접 측정법의 평가 | - |
dc.title.alternative | Direct Measurement of High-Density Lipoprotein Cholesterol Evaluated | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 김영아 | - |
dc.contributor.googleauthor | 임환섭 | - |
dc.contributor.googleauthor | 이정운 | - |
dc.contributor.googleauthor | 김정호 | - |
dc.contributor.googleauthor | 권오헌 | - |
dc.contributor.localId | A00903 | - |
dc.relation.journalcode | J01988 | - |
dc.contributor.alternativeName | Kim, Jeong Ho | - |
dc.contributor.affiliatedAuthor | 김정호 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 529 | - |
dc.citation.endPage | 533 | - |
dc.identifier.bibliographicCitation | Korean Journal of Clinical Pathology (대한임상병리학회지), Vol.18(4) : 529-533, 1998 | - |
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