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The effect of chronic coffee drinking on blood pressure: a meta-analysis of controlled clinical trials

Authors
 Sun Ha Jee  ;  Jiang He  ;  Paul K. Whelton  ;  Il Suh  ;  Michael J. Klag 
Citation
 HYPERTENSION, Vol.33(2) : 647-652, 1998 
Journal Title
 HYPERTENSION 
ISSN
 0194-911X 
Issue Date
1998
MeSH
Adolescent ; Adult ; Age Factors ; Aged ; Blood Pressure/drug effects* ; Coffee/adverse effects* ; Female ; Humans ; Male ; Middle Aged ; Randomized Controlled Trials as Topic
Keywords
Words: blood pressure ; coffee ; meta-analysis ; clinical trials
Abstract
We sought to assess the effect of coffee consumption on blood pressure in humans. Our data sources included a MEDLINE search of the literature published before December 1997, bibliography review, and expert consultation. We selected controlled trials in which coffee consumption was the only difference between the intervention and control groups, mean blood pressure change was reported for each group or period, and treatment lasted for >24 hours. Of 36 studies initially identified, 11 (522 participants) met these inclusion criteria. Information on sample size, study design, participant characteristics (gender, race, age, baseline blood pressure, and antihypertensive medications), and treatment results were abstracted by 3 reviewers using a standardized protocol. Treatment effect of coffee consumption on blood pressure was estimated with the use of a random-effects model. In the 11 trials, median duration was 56 days (range, 14 to 79 days), and median dose of coffee was 5 cups/d. Systolic and diastolic blood pressure increased by 2.4 (range, 1.0 to 3.7) mm Hg and 1.2 (range, 0.4 to 2.1) mm Hg, respectively, with coffee treatment compared with control. Multiple linear regression analysis identified an independent, positive relationship between cups of coffee consumed and subsequent change in systolic blood pressure, independent of age of study participants and study design characteristics. The effect of coffee drinking on systolic and diastolic blood pressure was greater in trials with younger participants. Our findings provide support for a relationship between coffee consumption and higher blood pressure. Trials of coffee cessation of longer duration and in persons with hypertension should be performed.
Full Text
https://www.ahajournals.org/doi/full/10.1161/01.hyp.33.2.647
DOI
10.1161/01.hyp.33.2.647
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Preventive Medicine and Public Health (예방의학교실) > 1. Journal Papers
4. Graduate School of Public Health (보건대학원) > Graduate School of Public Health (보건대학원) > 1. Journal Papers
Yonsei Authors
Suh, Il(서일) ORCID logo https://orcid.org/0000-0002-9689-7849
Jee, Sun Ha(지선하) ORCID logo https://orcid.org/0000-0001-9519-3068
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176933
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