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Localized mucosal involvement and severe pulmonary involvement in a young patient with paraneoplastic pemphigus associated with Castleman's tumour

Authors
 S-C. KIM  ;  S.N. CHANG  ;  I.J. LEE  ;  S.D. PARK  ;  E.T .JEONG  ;  C.W. LEE  ;  C.M. AHN  ;  G.J. ANHALT 
Citation
 BRITISH JOURNAL OF DERMATOLOGY, Vol.138(4) : 667-671, 1998 
Journal Title
 BRITISH JOURNAL OF DERMATOLOGY 
ISSN
 0007-0963 
Issue Date
1998
MeSH
Adult ; Bronchiolitis Obliterans/etiology* ; Bronchiolitis Obliterans/pathology ; Castleman Disease/complications* ; Female ; Genital Diseases, Female/etiology ; Humans ; Oral Ulcer/etiology ; Oral Ulcer/pathology ; Pemphigus/etiology* ; Ulcer/etiology* ; Ulcer/pathology
Abstract
We describe a 19-year-old female patient who developed recurrent ulcerations limited to the orogenital mucosa for the last 3 years. She also developed dyspnoea 5 months after the onset of the orogenital lesions. Castleman's tumour of the retroperitoneum was found incidentally during routine physical examination. The diagnosis of paraneoplastic pemphigus (PNP) was made by pathological and immunological studies. The orogenital ulceration responded well to corticosteroid therapy, but severe bronchiolitis obliterans progressed despite intensive care. The patient eventually died from respiratory failure. This case demonstrates the diversity of clinical features of paraneoplastic pemphigus.
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2133.1998.02183.x
DOI
10.1046/j.1365-2133.1998.02183.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Soo Chan(김수찬) ORCID logo https://orcid.org/0000-0002-2327-4755
Ahn, Chul Min(안철민)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176801
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