Cited 18 times in

Complement-fixing abilities and IgG subclasses of autoantibodies in epidermolysis bullosa acquisita

DC Field Value Language
dc.contributor.author김수찬-
dc.date.accessioned2020-07-02T17:07:26Z-
dc.date.available2020-07-02T17:07:26Z-
dc.date.issued1998-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176607-
dc.description.abstractEpidermolysis bullosa acquisita (EBA) is an autoimmune-mediated subepidermal bullous disease in which the target of the autoantibodies is type VII collagen, a major component of anchoring fibrils. The purpose of this study was to evaluate the complement-fixing abilities and IgG subclass distribution of autoantibodies in EBA, and to also attempt to investigate the relation between inflammation, complement fixation and IgG subclass distribution in EBA patients. Only 2 sera of 18 patients (11%) showed weak complement-fixing abilities. IgG1 and IgG4 were the most frequently and intensely stained IgG subclasses in EBA sera. We could not find any relationship between the clinico-pathologic types, complement-fixing abilities and IgG subclasses in EBA. These results suggested that complement activation may not be a key factor of bulla formation in EBA.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAutoantibodies/classification*-
dc.subject.MESHComplement System Proteins/immunology*-
dc.subject.MESHEpidermolysis Bullosa Acquisita/immunology*-
dc.subject.MESHFemale-
dc.subject.MESHFluorescent Antibody Technique-
dc.subject.MESHHumans-
dc.subject.MESHImmunoglobulin G/classification*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.titleComplement-fixing abilities and IgG subclasses of autoantibodies in epidermolysis bullosa acquisita-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Dermatology (피부과학교실)-
dc.contributor.googleauthorHeun Jung Cho-
dc.contributor.googleauthorIl Joo Lee-
dc.contributor.googleauthorSoo Chan Kim-
dc.identifier.doi10.3349/ymj.1998.39.4.339-
dc.contributor.localIdA00637-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid9752800-
dc.contributor.alternativeNameKim, Soo Chan-
dc.contributor.affiliatedAuthor김수찬-
dc.citation.volume39-
dc.citation.number4-
dc.citation.startPage339-
dc.citation.endPage344-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.39(4) : 339-344, 1998-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers

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