Cited 18 times in
Complement-fixing abilities and IgG subclasses of autoantibodies in epidermolysis bullosa acquisita
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김수찬 | - |
dc.date.accessioned | 2020-07-02T17:07:26Z | - |
dc.date.available | 2020-07-02T17:07:26Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176607 | - |
dc.description.abstract | Epidermolysis bullosa acquisita (EBA) is an autoimmune-mediated subepidermal bullous disease in which the target of the autoantibodies is type VII collagen, a major component of anchoring fibrils. The purpose of this study was to evaluate the complement-fixing abilities and IgG subclass distribution of autoantibodies in EBA, and to also attempt to investigate the relation between inflammation, complement fixation and IgG subclass distribution in EBA patients. Only 2 sera of 18 patients (11%) showed weak complement-fixing abilities. IgG1 and IgG4 were the most frequently and intensely stained IgG subclasses in EBA sera. We could not find any relationship between the clinico-pathologic types, complement-fixing abilities and IgG subclasses in EBA. These results suggested that complement activation may not be a key factor of bulla formation in EBA. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Autoantibodies/classification* | - |
dc.subject.MESH | Complement System Proteins/immunology* | - |
dc.subject.MESH | Epidermolysis Bullosa Acquisita/immunology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Fluorescent Antibody Technique | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Immunoglobulin G/classification* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.title | Complement-fixing abilities and IgG subclasses of autoantibodies in epidermolysis bullosa acquisita | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Dermatology (피부과학교실) | - |
dc.contributor.googleauthor | Heun Jung Cho | - |
dc.contributor.googleauthor | Il Joo Lee | - |
dc.contributor.googleauthor | Soo Chan Kim | - |
dc.identifier.doi | 10.3349/ymj.1998.39.4.339 | - |
dc.contributor.localId | A00637 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 9752800 | - |
dc.contributor.alternativeName | Kim, Soo Chan | - |
dc.contributor.affiliatedAuthor | 김수찬 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 339 | - |
dc.citation.endPage | 344 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.39(4) : 339-344, 1998 | - |
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