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Sensory and motor dysfunction assessed by anorectal manometry in uterine cervical carcinoma patients with radiation-induced late rectal complication

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dc.contributor.author박효진-
dc.contributor.author성진실-
dc.contributor.author이용찬-
dc.date.accessioned2020-07-02T17:00:36Z-
dc.date.available2020-07-02T17:00:36Z-
dc.date.issued1998-
dc.identifier.issn0360-3016-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176522-
dc.description.abstractPURPOSE: To investigate the effects of radiation on anorectal function in patients with carcinoma of the uterine cervix. METHODS AND MATERIALS: Anorectal manometry was carried out on 24 patients (complication group) with late radiation proctitis. All of the manometric data from these patients were compared with those from 24 age-matched female volunteers (control group), in whom radiation treatment had not yet been performed. RESULTS: Regardless of the severity of proctitis symptoms, 25% of patients demonstrated all their manometric data within the normal range, but 75% of patients exhibited one or more abnormal manometric parameters for sensory or motor functions. Six patients (25%) had an isolated sensory dysfunction, eight patients (33.3%) had an isolated motor dysfunction, and four patients (16.7%) had combined disturbances of both sensory and motor functions. The maximum tolerable volume, the minimal threshold volume, and the urgent volume in the complication group were significantly reduced compared with those in the control group. The mean squeeze pressure in the complication group was significantly reduced, whereas the mean resting pressure and anal sphincter length were unchanged. CONCLUSIONS: Physiologic changes of the anorectum in patients with late radiation proctitis seem to be caused by a variety of sensory and/or motor dysfunctions in which many different mechanisms are working together. The reduced rectal reservoir capacity and impaired sensory functions were crucial factors for functional disorder in such patients. In addition, radiation damage to the external anal sphincter muscle was considered to be an important cause of motor dysfunction.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier Science Inc.-
dc.relation.isPartOfINTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAnal Canal/physiopathology*-
dc.subject.MESHAnal Canal/radiation effects-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHManometry-
dc.subject.MESHMiddle Aged-
dc.subject.MESHProctitis/physiopathology*-
dc.subject.MESHRadiation Injuries/physiopathology*-
dc.subject.MESHSensation Disorders/physiopathology*-
dc.subject.MESHUterine Cervical Neoplasms/radiotherapy*-
dc.titleSensory and motor dysfunction assessed by anorectal manometry in uterine cervical carcinoma patients with radiation-induced late rectal complication-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorGwi Eon Kim-
dc.contributor.googleauthorJohn Jihoon Lim-
dc.contributor.googleauthorWon Park-
dc.contributor.googleauthorHee Chul Park-
dc.contributor.googleauthorEun Ji Chung-
dc.contributor.googleauthorJinsil Seong-
dc.contributor.googleauthorChang Ok Suh-
dc.contributor.googleauthorYong Chan Lee-
dc.contributor.googleauthorHyo Jin Park-
dc.identifier.doi10.1016/s0360-3016(98)00094-7-
dc.contributor.localIdA01774-
dc.contributor.localIdA01956-
dc.contributor.localIdA02988-
dc.relation.journalcodeJ01157-
dc.identifier.eissn1879-355X-
dc.identifier.pmid9652846-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0360301698000947-
dc.contributor.alternativeNamePark, Hyo Jin-
dc.contributor.affiliatedAuthor박효진-
dc.contributor.affiliatedAuthor성진실-
dc.contributor.affiliatedAuthor이용찬-
dc.citation.volume41-
dc.citation.number4-
dc.citation.startPage835-
dc.citation.endPage841-
dc.identifier.bibliographicCitationINTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, Vol.41(4) : 835-841, 1998-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

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