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Primary lymphoma of the eye

DC FieldValueLanguage
dc.contributor.author양우익-
dc.date.accessioned2020-07-02T16:51:45Z-
dc.date.available2020-07-02T16:51:45Z-
dc.date.issued1998-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/176411-
dc.description.abstractLymphomas in the eye tend to be localized and to have a better prognosis. We reviewed the clinical presentation, treatment outcome and complications of primary lymphomas of the eye at a single institute focusing on the clinical significance of adequate staging and the prognostic value of pathological subtypes. Twenty-four patients with lymphoproliferative lesion of the eye were treated and followed up. The orbit was the most commonly involved site. Twenty-one patients had unilateral diseases and three patients had bilateral. Histological findings revealed 22 malignant lymphomas, one inflammatory pseudotumor and one atypical lymphoid hyperplasia. Using the NCI Working Formulation, most of the malignant lymphomas were primarily low grade: diffuse small lymphocytic, 15; diffuse small cleaved three; diffuse large cell, three; and diffuse mixed, one. The stages of lymphoma were IAE in 21 patients, IBE in one patient, and IIAE in two patients. Twenty-five of the 27 treated eyes remained disease-free during the median follow-up period of 16 months. Nineteen patients received radiotherapy, five patients received chemo-radiotherapy and one patient received only surgical excision. Two patients relapsed outside the treated field. None of the patients complained of severe dry eye syndrome or cataract formation. In conclusion, after complete staging work-up, locally-confined low grade orbital lymphomas can be up to 90% controlled with radiotherapy alone. By contrast, combined treatment is advised in patients with intermediate and high grade lesions.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdolescent-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAntineoplastic Combined Chemotherapy Protocols/therapeutic use-
dc.subject.MESHCombined Modality Therapy-
dc.subject.MESHEye Neoplasms/drug therapy-
dc.subject.MESHEye Neoplasms/pathology*-
dc.subject.MESHEye Neoplasms/radiotherapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHLymphoma/drug therapy-
dc.subject.MESHLymphoma/pathology*-
dc.subject.MESHLymphoma/radiotherapy*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHSurvival Analysis-
dc.titlePrimary lymphoma of the eye-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pathology (병리학교실)-
dc.contributor.googleauthorJee Sook Hahn-
dc.contributor.googleauthorChang Ok Suh-
dc.contributor.googleauthorSang Yeul Lee-
dc.contributor.googleauthorWoo Ick Yang-
dc.identifier.doi10.3349/ymj.1998.39.3.196-
dc.contributor.localIdA02300-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid9664823-
dc.contributor.alternativeNameYang, Woo Ick-
dc.contributor.affiliatedAuthor양우익-
dc.citation.volume39-
dc.citation.number3-
dc.citation.startPage196-
dc.citation.endPage201-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.39(3) : 196-201, 1998-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers

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