Cited 13 times in
c-erbB-2 oncoprotein assay in ovarian carcinoma and its clinical correlation with prognostic factors
DC Field | Value | Language |
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dc.contributor.author | 김영태 | - |
dc.date.accessioned | 2020-07-02T16:51:27Z | - |
dc.date.available | 2020-07-02T16:51:27Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 0304-3835 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176406 | - |
dc.description.abstract | Overexpression of the c-erbB-2 oncoprotein has been detected in human adenocarcinoma of the breast, cervix and salivary gland, in all of which an association between the overexpression of the c-erbB-2 and a poor prognosis of the disease has been reported. However, the prognostic role of c-erbB-2 oncoprotein in ovarian carcinoma remains controversial. We measured c-erbB-2 oncoprotein with an enzyme-linked immunosorbent assay (ELISA). Patients with invasive ovarian cancer were found to have significantly higher median c-erbB-2 oncoprotein expression than patients with either benign ovarian cyst (P = 0.002) or control groups (P = 0.001). Overexpression of c-erbB-2 oncoprotein was found in seven (21.9%) of 32 epithelial ovarian cancers. Our results suggest that quantitative analysis of c-erbB-2 oncoprotein may be used to define the prognostic significance of ovarian carcinoma. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Science Ireland | - |
dc.relation.isPartOf | CANCER LETTERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Carcinoma/metabolism* | - |
dc.subject.MESH | Carcinoma/pathology | - |
dc.subject.MESH | Carcinoma/surgery | - |
dc.subject.MESH | Enzyme-Linked Immunosorbent Assay | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Ovarian Neoplasms/metabolism* | - |
dc.subject.MESH | Ovarian Neoplasms/pathology | - |
dc.subject.MESH | Ovarian Neoplasms/surgery | - |
dc.subject.MESH | Pelvis | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Receptor, ErbB-2/analysis* | - |
dc.title | c-erbB-2 oncoprotein assay in ovarian carcinoma and its clinical correlation with prognostic factors | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics and Gynecology (산부인과학교실) | - |
dc.contributor.googleauthor | Young Tae Kim | - |
dc.contributor.googleauthor | Jae Wook Kim | - |
dc.contributor.googleauthor | Jung Woon Lee | - |
dc.identifier.doi | 10.1016/s0304-3835(98)00162-1 | - |
dc.contributor.localId | A00729 | - |
dc.relation.journalcode | J00448 | - |
dc.identifier.eissn | 1872-7980 | - |
dc.identifier.pmid | 10397458 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0304383598001621 | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | 김영태 | - |
dc.citation.volume | 132 | - |
dc.citation.number | 1~2 | - |
dc.citation.startPage | 91 | - |
dc.citation.endPage | 97 | - |
dc.identifier.bibliographicCitation | CANCER LETTERS, Vol.132(1~2) : 91-97, 1998 | - |
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