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전신성 홍반성 루푸스 환자에서 임상적 질병 활성도와 혈청 인터루킨 8과의 연관성
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.contributor.author | 박용범 | - |
dc.contributor.author | 이수곤 | - |
dc.date.accessioned | 2020-07-02T16:46:04Z | - |
dc.date.available | 2020-07-02T16:46:04Z | - |
dc.date.issued | 1998 | - |
dc.identifier.issn | 1226-329X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176346 | - |
dc.description.abstract | Objectives : To evaluate seam Interleukin 8 (IL-8) as a predictor of disease activity in SLE and to provide insight into the potential role of IL-8 in the pathogenesis of SLE. Methods : Sixty-four paired sera from the 32 SLE patients and 10 healthy control sera were obtained. Serum IL-8 levels were determined by ELISA technique. Tests for other laboratory parameters, such as circulating immune complex (CIC), C3, C4, ANA, anti-dsDNA, Hb, Hct, leukocyte, lymphocyte, platelet and ESR were per(orbed for every sample coincidently with) assessment of clinical disease activity by the Lahita scales. Results ; We found that serum IL-8 levels in SLE patients were significantly higher than those of healthy controls. serum IL-8 levels significantly correlated with clinical disease activity. Serum IL-8 levels correlated with CIC, but it had no correlation with other laboratory parameters. Conclusion : These findings suggest that serum IL-8 can be used as a marker of disease activity in patients with SLE. These results may have implication in the pathogenesis of SLE. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한내과학회 | - |
dc.relation.isPartOf | Korean Journal of Medicine (대한내과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 전신성 홍반성 루푸스 환자에서 임상적 질병 활성도와 혈청 인터루킨 8과의 연관성 | - |
dc.title.alternative | Correlation of serum Interleukin 8 with clinical disease activity in systemic lupus erythematosus (SLE) | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | 이원기 | - |
dc.contributor.googleauthor | 송창호 | - |
dc.contributor.googleauthor | 박용범 | - |
dc.contributor.googleauthor | 이충원 | - |
dc.contributor.googleauthor | 서창희 | - |
dc.contributor.googleauthor | 이찬희 | - |
dc.contributor.googleauthor | 이지수 | - |
dc.contributor.googleauthor | 김동수 | - |
dc.contributor.googleauthor | 이수곤 | - |
dc.contributor.localId | A00405 | - |
dc.contributor.localId | A01579 | - |
dc.contributor.localId | A02889 | - |
dc.relation.journalcode | J02060 | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.affiliatedAuthor | 김동수 | - |
dc.contributor.affiliatedAuthor | 박용범 | - |
dc.contributor.affiliatedAuthor | 이수곤 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 770 | - |
dc.citation.endPage | 777 | - |
dc.identifier.bibliographicCitation | Korean Journal of Medicine (대한내과학회지), Vol.54(6) : 770-777, 1998 | - |
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