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습관성 자연유산을 경험한 130 쌍의 부부에서 시행한 세포유전학적 검사 결과 분석

Other Titles
 A Cytogenetic Study of 130 Couples with Recurrent Spontaneous Abortion 
Authors
 이경아  ;  오기진  ;  윤갑준 
Citation
 Korean Journal of Clinical Pathology (대한임상병리학회지), Vol.18(3) : 476-479, 1998 
Journal Title
 Korean Journal of Clinical Pathology (대한임상병리학회지) 
ISSN
 1015-6445 
Issue Date
1998
Abstract
Background :Chromosomal aberration of a couple can lead to recurrent miscarriage and it has been accounted for 2-10% of recurrent spontaneous abortions in the Caucasian population The purpose of this stuffy is to evaluate the frequency of chromosomal abnormalities in couples having fetal losses. We also attempted to define the relationship of those chromosome rearrangements with the presence or absence of stillborn fetus or malformed live child Method :A total of 130 couples with two or more spontaneous abortions were studied. Chromosome studios were performed on metaphases using standard peripheral lymphocyte culture technique Result :Ten (77%) chromosomal abnormalities were detected, 7 (5,4%) in women and 3 23%) in men. The chance of finding chromosomal abnormality in couples with stillborn fetus or malformed live child was higher than in couples with spontaneous abortions but no other adverse event, but the difference was not statistically significant. Conclusion :Cytogenetic analysis was indicated in couples with recurrent spontaneous abortions The chance of chromosomal abnormality in couples with stillborn fetus or malformed live child was higher.
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kyung A(이경아) ORCID logo https://orcid.org/0000-0001-5320-6705
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/176316
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