복합적 염색체 이상을 보인 비분비형 형질세포백 혈병 1례

Abstract

We report a case of non-secretory plasma cell leukemia with complex chromosomal abnormalities including t(11;14)(q13;q32). A 57-year-old man was admitted to hospital due to anemia, thrombocytopenia and renal insufficiency. Bone marrow examination and peripheral blood smear revealed a large number of immature plasma cells with positivity for CD38. Monoclonal gammopathy or abnormal paraproteins were not observed in serum protein electrophoresis and immunofixation. The cytogenetic analysis showed complex chromosomal abnormalities[45,XY,-1,t(11;14)(q13;q32),t(12;17)(p13;q21)]. He was died of adult respiratory distress syndrome on the 6th hospital day.