Cited 20 times in
Long-term Fine Particulate Matter Exposure and Cardiovascular Mortality in the General Population: A Nationwide Cohort Study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김인수 | - |
dc.contributor.author | 김종윤 | - |
dc.contributor.author | 김태훈 | - |
dc.contributor.author | 박희남 | - |
dc.contributor.author | 양필성 | - |
dc.contributor.author | 엄재선 | - |
dc.contributor.author | 유희태 | - |
dc.contributor.author | 이문형 | - |
dc.contributor.author | 이진애 | - |
dc.contributor.author | 정보영 | - |
dc.date.accessioned | 2020-06-17T00:41:26Z | - |
dc.date.available | 2020-06-17T00:41:26Z | - |
dc.date.issued | 2020-05 | - |
dc.identifier.issn | 0914-5087 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/176086 | - |
dc.description.abstract | Background: Although eastern Asian countries are exposed to high levels of air pollution, the impact of long-term exposures to fine particulate matter (PM2.5) air pollution on all-cause and cardiovascular mortality is not well identified. We assessed the relationship between long-term PM2.5 exposure and all-cause/cardiovascular mortalities. Methods: We included 436,933 subjects who received national health examinations from the Korean National Health Insurance Service-based National Sample Cohort. We matched subjects' residential-address areas with hourly-measurements of PM2.5 concentration data. We estimated the risk of mortality with average PM2.5 exposure during the study period using a Cox proportional-hazards model. Results: During 1,683,271 person·years, all-cause and cardiovascular mortalities were observed in 6432 and 1603 subjects (382 and 95 per 100,000 person·years, respectively). An increase in 10 μg/m3 in PM2.5 was associated with increases in all-cause and cardiovascular mortalities by 3.4 % [2.7-4.1] and 4.7 % [3.6-5.8], respectively (each p < 0.001). PM2.5 was linearly and significantly correlated with these all-cause and cardiovascular mortalities above 18 μg/m3 of PM2.5 (p < 0.001), but it was not significant below 18 μg/m3 of PM2.5. To investigate the specific PM2.5 concentration for raising cardiovascular mortality more, we analyzed the sensitivities/specificities for different PM2.5 levels, and 18 μg/m3 showed the highest Youden's index (sensitivity + specificity-1) with c-index of 0.85 (0.84-0.86). PM2.5 effect on all-cause mortality was more profound in subjects with previous myocardial infarction compared to the opposite population. Conclusions: In the Korean general population exposed to high-air pollution, long-term PM2.5 exposure was linearly associated with increased risk for all-cause and cardiovascular mortality, especially above 18 μg/m3 of PM2.5. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Japanese, English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Long-term Fine Particulate Matter Exposure and Cardiovascular Mortality in the General Population: A Nationwide Cohort Study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | In-Soo Kim | - |
dc.contributor.googleauthor | Pil-Sung Yang | - |
dc.contributor.googleauthor | Jinae Lee | - |
dc.contributor.googleauthor | Hee Tae Yu | - |
dc.contributor.googleauthor | Tae-Hoon Kim | - |
dc.contributor.googleauthor | Jae-Sun Uhm | - |
dc.contributor.googleauthor | Jong-Youn Kim | - |
dc.contributor.googleauthor | Hui-Nam Pak | - |
dc.contributor.googleauthor | Moon-Hyoung Lee | - |
dc.contributor.googleauthor | Boyoung Joung | - |
dc.identifier.doi | 10.1016/j.jjcc.2019.11.004 | - |
dc.contributor.localId | A00840 | - |
dc.contributor.localId | A00926 | - |
dc.contributor.localId | A01085 | - |
dc.contributor.localId | A01776 | - |
dc.contributor.localId | A02323 | - |
dc.contributor.localId | A02337 | - |
dc.contributor.localId | A02535 | - |
dc.contributor.localId | A02766 | - |
dc.contributor.localId | A04641 | - |
dc.contributor.localId | A03609 | - |
dc.relation.journalcode | J01287 | - |
dc.identifier.eissn | 1876-4738 | - |
dc.identifier.pmid | 31839460 | - |
dc.subject.keyword | Air pollution | - |
dc.subject.keyword | Fine particulate matter | - |
dc.subject.keyword | General population | - |
dc.subject.keyword | Long-term exposure | - |
dc.subject.keyword | Mortality | - |
dc.contributor.alternativeName | Kim, In-Soo | - |
dc.contributor.affiliatedAuthor | 김인수 | - |
dc.contributor.affiliatedAuthor | 김종윤 | - |
dc.contributor.affiliatedAuthor | 김태훈 | - |
dc.contributor.affiliatedAuthor | 박희남 | - |
dc.contributor.affiliatedAuthor | 양필성 | - |
dc.contributor.affiliatedAuthor | 엄재선 | - |
dc.contributor.affiliatedAuthor | 유희태 | - |
dc.contributor.affiliatedAuthor | 이문형 | - |
dc.contributor.affiliatedAuthor | 이진애 | - |
dc.contributor.affiliatedAuthor | 정보영 | - |
dc.citation.volume | 75 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 549 | - |
dc.citation.endPage | 558 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CARDIOLOGY, Vol.75(5) : 549-558, 2020-05 | - |
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