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Four-year Follow-Up Results of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor
DC Field | Value | Language |
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dc.contributor.author | 장진우 | - |
dc.contributor.author | 정나영 | - |
dc.date.accessioned | 2020-06-04T08:45:48Z | - |
dc.date.available | 2020-06-04T08:45:48Z | - |
dc.date.issued | 2019-05 | - |
dc.identifier.issn | 0885-3185 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175872 | - |
dc.description.abstract | Background: Following the emergence of magnetic resonance-guided focused ultrasound as a promising tool for movement disorder surgery, thalamotomy for essential tremor using this technique has become a useful tool based on its efficacy and lack of adverse effects. Here, we summarize the 4-year results of previous reports focusing on the durability of effectiveness of magnetic resonance-guided focused ultrasound thalamotomy for essential tremor. Methods: From October 2013 to August 2014, 15 patients with intractable essential tremor were enrolled. Twelve of them completed clinical assessment through 4 years of postoperative follow-up. Tremor severity, task performance, and disability were measured using the Clinical Rating Scale of Tremor. Results: The mean age of the 12 patients was 61.7 ± 8.1 years. Maximally delivered energy was 15,552.4 ± 6574.1 joules. The mean number of sonications was 17.3 ± 1.6. The mean postoperative lesion volume was 82.6 ± 29.023 mm3 and in 1 year was a mean of 9.667 ± 8.573 mm3 . Four years postoperatively, improvement of the hand tremor score was 56%, that of the disability score was 63%, that of the postural score was 70%, and that of the action score was 63% compared with baseline; all improvements were significant and sustained over the 4-year period after thalamotomy. There was no permanent adverse effect throughout the 4-year follow-up period. Conclusions: Magnetic resonance-guided focused ultrasound thalamotomy exhibits sustained clinical efficacy 4 years after the treatment of intractable essential tremor. Adverse events are generally transient. A large cohort of patients who have undergone magnetic resonance-guided focused ultrasound thalamotomy with longer follow-up is needed to confirm our findings. © 2019 International Parkinson and Movement Disorder Society. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-Liss | - |
dc.relation.isPartOf | MOVEMENT DISORDERS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Essential Tremor / surgery* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | High-Intensity Focused Ultrasound Ablation / methods* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Magnetic Resonance Imaging | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Neurosurgical Procedures | - |
dc.subject.MESH | Surgery, Computer-Assisted / methods* | - |
dc.subject.MESH | Thalamus / surgery* | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Four-year Follow-Up Results of Magnetic Resonance-Guided Focused Ultrasound Thalamotomy for Essential Tremor | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Yong-Sook Park | - |
dc.contributor.googleauthor | Na Young Jung | - |
dc.contributor.googleauthor | Young Cheol Na | - |
dc.contributor.googleauthor | Jin Woo Chang | - |
dc.identifier.doi | 10.1002/mds.27637 | - |
dc.contributor.localId | A03484 | - |
dc.contributor.localId | A05272 | - |
dc.relation.journalcode | J02275 | - |
dc.identifier.eissn | 1531-8257 | - |
dc.identifier.pmid | 30759322 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1002/mds.27637 | - |
dc.subject.keyword | essential tremor | - |
dc.subject.keyword | high-intensity focused ultrasound | - |
dc.subject.keyword | thalamotomy | - |
dc.contributor.alternativeName | Chang, Jin Woo | - |
dc.contributor.affiliatedAuthor | 장진우 | - |
dc.contributor.affiliatedAuthor | 정나영 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 727 | - |
dc.citation.endPage | 734 | - |
dc.identifier.bibliographicCitation | MOVEMENT DISORDERS, Vol.34(5) : 727-734, 2019-05 | - |
dc.identifier.rimsid | 64413 | - |
dc.type.rims | ART | - |
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