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Efficacy of a Novel Annular Closure Device After Lumbar Discectomy in Korean Patients : A 24-Month Follow-Up of a Randomized Controlled Trial
DC Field | Value | Language |
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dc.contributor.author | 신동아 | - |
dc.date.accessioned | 2020-06-04T08:42:34Z | - |
dc.date.available | 2020-06-04T08:42:34Z | - |
dc.date.issued | 2019-11 | - |
dc.identifier.issn | 2005-3711 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175852 | - |
dc.description.abstract | Objective: Lumbar discectomy is an effective treatment for lumbar disc herniation (LDH); however, up to 2-18% of patients with LDH have experienced recurrent disc herniation. The purpose of this study was to evaluate the efficacy of a novel annular closure device (ACD) for preventing LDH recurrence and re-operation compared with that of conventional lumbar discectomy (CLD). Methods: In this prospective randomized controlled trial, we compared CLD with discectomy utilizing the Barricaid® (Intrinsic Therapeutics, Inc., Woburn, MA, USA) ACD. Primary radiologic outcomes included disc height, percentage of preoperative disc height maintained, and re-herniation rates. Additional clinical outcomes included visual analog scale (VAS) scores for back and leg pain, Oswestry Disability Index (ODI) scores, and 12-item short-form health survey (SF-12) quality of life scores. Outcomes were measured at preoperation and at 1 week, 1, 3, 6, 12, and 24 months postoperation. Results: Sixty patients (30 CLD, 30 ACD) were enrolled in this study. At 24-month follow-up, the disc height in the ACD group was significantly greater than that in the CLD group (11.4±1.5 vs. 10.2±1.2 mm, p=0.006). Re-herniation occurred in one patient in the ACD group versus six patients in the CLD group (χ2=4.04, p=0.044). Back and leg VAS scores, ODI scores, and SF-12 scores improved significantly in both groups compared with preoperative scores in the first 7 days following surgery and remained at significantly improved levels at a 24-month follow-up. However, no statistical difference was found between the two groups. Conclusion: Lumbar discectomy with the Barricaid® (Intrinsic Therapeutics, Inc.) ACD is more effective at maintaining disc height and preventing re-herniation compared with conventional discectomy. Our results suggest that adoption of ACD in lumbar discectomy can help improve the treatment outcome. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Neurosurgical Society | - |
dc.relation.isPartOf | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Efficacy of a Novel Annular Closure Device After Lumbar Discectomy in Korean Patients : A 24-Month Follow-Up of a Randomized Controlled Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurosurgery (신경외과학교실) | - |
dc.contributor.googleauthor | Pyung Goo Cho | - |
dc.contributor.googleauthor | Dong Ah Shin | - |
dc.contributor.googleauthor | Sang Hyuk Park | - |
dc.contributor.googleauthor | Gyu Yeul Ji | - |
dc.identifier.doi | 10.3340/jkns.2019.0071 | - |
dc.contributor.localId | A02092 | - |
dc.relation.journalcode | J01520 | - |
dc.identifier.eissn | 1598-7876 | - |
dc.identifier.pmid | 31679318 | - |
dc.subject.keyword | Intervertebral disc disease | - |
dc.subject.keyword | Discectomy | - |
dc.subject.keyword | Herniated disc | - |
dc.subject.keyword | Barricaid | - |
dc.contributor.alternativeName | Shin, Dong A | - |
dc.contributor.affiliatedAuthor | 신동아 | - |
dc.citation.volume | 62 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 691 | - |
dc.citation.endPage | 699 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN NEUROSURGICAL SOCIETY, Vol.62(6) : 691-699, 2019-11 | - |
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