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Magnetic Resonance-Guided Focused Ultrasound in Neurosurgery: Taking Lessons From the Past to Inform the Future

DC FieldValueLanguage
dc.contributor.author장진우-
dc.contributor.author정나영-
dc.date.accessioned2020-06-04T08:42:12Z-
dc.date.available2020-06-04T08:42:12Z-
dc.date.issued2018-10-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/175849-
dc.description.abstractMagnetic resonance-guided focused ultrasound (MRgFUS) is a new emerging neurosurgical procedure applied in a wide range of clinical fields. It can generate high-intensity energy at the focal zone in deep body areas without requiring incision of soft tissues. Although the effectiveness of the focused ultrasound technique had not been recognized because of the skull being a main barrier in the transmission of acoustic energy, the development of hemispheric distribution of ultrasound transducer phased arrays has solved this issue and enabled the performance of true transcranial procedures. Advanced imaging technologies such as magnetic resonance thermometry could enhance the safety of MRgFUS. The current clinical applications of MRgFUS in neurosurgery involve stereotactic ablative treatments for patients with essential tremor, Parkinson's disease, obsessive-compulsive disorder, major depressive disorder, or neuropathic pain. Other potential treatment candidates being examined in ongoing clinical trials include brain tumors, Alzheimer's disease, and epilepsy, based on MRgFUS abilities of thermal ablation and opening the blood-brain barrier. With the development of ultrasound technology to overcome the limitations, MRgFUS is gradually expanding the therapeutic field for intractable neurological disorders and serving as a trail for a promising future in noninvasive and safe neurosurgical care.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisher대한의학회(The Korean Academy of Medical Sciences)-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleMagnetic Resonance-Guided Focused Ultrasound in Neurosurgery: Taking Lessons From the Past to Inform the Future-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학교실)-
dc.contributor.googleauthorNa Young Jung-
dc.contributor.googleauthorJin Woo Chang-
dc.identifier.doi10.3346/jkms.2018.33.e279-
dc.contributor.localIdA03484-
dc.contributor.localIdA05272-
dc.contributor.localIdA05272-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid30369860-
dc.subject.keywordAblation-
dc.subject.keywordHigh-Intensity Focused Ultrasound Ablation-
dc.subject.keywordMagnetic Resonance Imaging-
dc.subject.keywordNeurological Disorder-
dc.subject.keywordNeurosurgical Procedure-
dc.contributor.alternativeNameChang, Jin Woo-
dc.contributor.affiliatedAuthor장진우-
dc.contributor.affiliatedAuthor정나영-
dc.contributor.affiliatedAuthor정나영-
dc.citation.volume33-
dc.citation.number44-
dc.citation.startPagee279-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.33(44) : e279, 2018-10-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers

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