Cited 33 times in
Emergence of multidrug‑resistant Providencia rettgeri isolates co‑producing NDM‑1 carbapenemase and PER‑1 extended‑spectrum β‑lactamase causing a first outbreak in Korea
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 홍준성 | - |
dc.contributor.author | 정석훈 | - |
dc.contributor.author | 이혁민 | - |
dc.date.accessioned | 2020-04-16T01:35:03Z | - |
dc.date.available | 2020-04-16T01:35:03Z | - |
dc.date.issued | 2018 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175681 | - |
dc.description.abstract | BACKGROUND: Nosocomial outbreak due to carbapenem-resistant Enterobacteriaceae has become serious challenge to patient treatment and infection control. We describe an outbreak due to a multidrug-resistant Providencia rettgeri from January 2016 to January 2017 at a University Hospital in Seoul, Korea. METHODS: A total of eight non-duplicate P. rettgeri isolates were discovered from urine samples from eight patients having a urinary catheter and admitted in a surgical intensive care unit. The β-lactamase genes were identified using polymerase chain reaction and direct sequencing, and strain typing was done with pulsed-field gel electrophoresis (PFGE). RESULTS: All isolates showed high-level resistance to extended-spectrum cephalosporins, aztreonam, meropenem, ertapenem, ciprofloxacin, and amikacin. They harbored the blaNDM-1 carbapenemase and the blaPER-1 type extended-spectrum β-lactamases genes. PFGE revealed that all isolates from eight patients were closely related strains. CONCLUSIONS: The 13-month outbreak ended following reinforcement of infection control measures, including contact isolation precautions and environmental disinfection. This is the first report of an outbreak of a P. rettgeri clinical isolates co-producing NDM-1 and PER-1 β-lactamase. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS | - |
dc.publisher | ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS | - |
dc.relation.isPartOf | ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Anti-Bacterial Agents/pharmacology | - |
dc.subject.MESH | Bacterial Proteins/genetics | - |
dc.subject.MESH | Disease Outbreaks* | - |
dc.subject.MESH | Drug Resistance, Multiple, Bacterial/drug effects | - |
dc.subject.MESH | Drug Resistance, Multiple, Bacterial/genetics* | - |
dc.subject.MESH | Electrophoresis, Gel, Pulsed-Field/methods | - |
dc.subject.MESH | Enterobacteriaceae Infections/epidemiology* | - |
dc.subject.MESH | Enterobacteriaceae Infections/microbiology* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Genes, Bacterial/genetics | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intensive Care Units | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Microbial Sensitivity Tests | - |
dc.subject.MESH | Providencia/drug effects | - |
dc.subject.MESH | Providencia/genetics* | - |
dc.subject.MESH | Providencia/isolation & purification* | - |
dc.subject.MESH | Providencia/pathogenicity* | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Urinary Catheters/microbiology | - |
dc.subject.MESH | Urinary Tract Infections/epidemiology | - |
dc.subject.MESH | Urinary Tract Infections/microbiology | - |
dc.subject.MESH | Urine/microbiology | - |
dc.subject.MESH | beta-Lactamases/genetics | - |
dc.title | Emergence of multidrug‑resistant Providencia rettgeri isolates co‑producing NDM‑1 carbapenemase and PER‑1 extended‑spectrum β‑lactamase causing a first outbreak in Korea | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Saeam Shin | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Hyukmin Lee | - |
dc.contributor.googleauthor | Jun Sung Hong | - |
dc.contributor.googleauthor | Min‑Jeong Park | - |
dc.contributor.googleauthor | Wonkeun Song | - |
dc.identifier.doi | 10.1186/s12941-018-0272-y | - |
dc.contributor.localId | A04438 | - |
dc.contributor.localId | A03619 | - |
dc.contributor.localId | A03286 | - |
dc.relation.journalcode | J03795 | - |
dc.identifier.eissn | 1476-0711 | - |
dc.identifier.pmid | 29728111 | - |
dc.subject.keyword | NDM-1 | - |
dc.subject.keyword | Outbreak | - |
dc.subject.keyword | PER-1 | - |
dc.subject.keyword | Providencia rettgeri | - |
dc.subject.keyword | Urinary tract infection | - |
dc.contributor.alternativeName | Hong, Jun Sung | - |
dc.contributor.affiliatedAuthor | 홍준성 | - |
dc.contributor.affiliatedAuthor | 정석훈 | - |
dc.contributor.affiliatedAuthor | 이혁민 | - |
dc.citation.volume | 17 | - |
dc.citation.startPage | 20 | - |
dc.identifier.bibliographicCitation | ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, Vol.17 : 20, 2018 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.