Cited 23 times in
Predictive factors for bacteremia in febrile infants with urinary tract infection
DC Field | Value | Language |
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dc.contributor.author | 김동수 | - |
dc.contributor.author | 김문규 | - |
dc.contributor.author | 신재일 | - |
dc.contributor.author | 안종균 | - |
dc.contributor.author | 윤서희 | - |
dc.contributor.author | 이금화 | - |
dc.date.accessioned | 2020-04-13T16:53:45Z | - |
dc.date.available | 2020-04-13T16:53:45Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175556 | - |
dc.description.abstract | This study aimed to investigate the predictive factors of concomitant bacteremia occurring in febrile infants who initially presented with pyuria and fever, and were subsequently diagnosed with culture-proven urinary tract infection (UTI). We conducted a retrospective cohort study for January 2010-October 2018 that included infants younger than six months with febrile UTI at a tertiary hospital. The study included 463 patients, of whom 34 had a concomitant bacteremic UTI. Compared to those in the non-bacteremic urinary tract infection (UTI) group, the bacteremic UTI group had a lower mean age; higher levels of C-reactive protein (CRP), delta neutrophil index (DNI, reflects the fraction of immature granulocytes) and blood urea nitrogen (BUN); lower levels of hemoglobin (Hb) and albumin; and a lower platelet count. Vesicoureteral reflux (VUR) was detected nearly twice as often in patients with bacteremic UTI compared to those with non-bacteremic UTI (59.3% vs. 30.6%; P = 0.003). Univariate logistic analyses showed that age ≤90 days; higher DNI, CRP, and creatinine levels; lower Hb and albumin levels; and the presence of VUR were predictors for bacteremic UTI. On multivariate logistic regression analysis, age ≤90 days, higher DNI and CRP levels, and the presence of VUR were independent predictors of bacteremic UTI. The area under the receiver operating characteristic curve of the multivariate model was 0.859 (95% CI, 0.779-0.939; P < 0.001). Age ≤90 days, higher DNI and CRP values may help predict bacteremia of febrile infants younger than 6 months with UTI. Vesicoureteral reflux imaging is also recommended in infants with bacteremic UTI to evaluate VUR. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Nature Publishing Group | - |
dc.relation.isPartOf | SCIENTIFIC REPORTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Predictive factors for bacteremia in febrile infants with urinary tract infection | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Seo Hee Yoon | - |
dc.contributor.googleauthor | HyunDo Shin | - |
dc.contributor.googleauthor | Keum Hwa Lee | - |
dc.contributor.googleauthor | Moon Kyu Kim | - |
dc.contributor.googleauthor | Dong Soo Kim | - |
dc.contributor.googleauthor | Jong Gyun Ahn | - |
dc.contributor.googleauthor | Jae Il Shin | - |
dc.identifier.doi | 10.1038/s41598-020-61421-4 | - |
dc.contributor.localId | A00405 | - |
dc.contributor.localId | A05689 | - |
dc.contributor.localId | A02142 | - |
dc.contributor.localId | A02261 | - |
dc.contributor.localId | A02563 | - |
dc.contributor.localId | A04622 | - |
dc.relation.journalcode | J02646 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.pmid | 32161316 | - |
dc.contributor.alternativeName | Kim, Dong Soo | - |
dc.contributor.affiliatedAuthor | 김동수 | - |
dc.contributor.affiliatedAuthor | 김문규 | - |
dc.contributor.affiliatedAuthor | 신재일 | - |
dc.contributor.affiliatedAuthor | 안종균 | - |
dc.contributor.affiliatedAuthor | 윤서희 | - |
dc.contributor.affiliatedAuthor | 이금화 | - |
dc.citation.volume | 10 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | e4469 | - |
dc.identifier.bibliographicCitation | SCIENTIFIC REPORTS, Vol.10(1) : e4469, 2020 | - |
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