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Comparing laparoscopic and open pancreaticoduodenectomy in patients with pancreatic head cancer: oncologic outcomes and inflammatory scores

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dc.contributor.author강창무-
dc.contributor.author노승윤-
dc.contributor.author이우정-
dc.contributor.author최문석-
dc.contributor.author황호경-
dc.date.accessioned2020-04-13T16:51:26Z-
dc.date.available2020-04-13T16:51:26Z-
dc.date.issued2020-
dc.identifier.issn1868-6974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/175540-
dc.description.abstractBACKGROUND: Both the technical and oncological safety of laparoscopic pancreaticoduodenectomy (LPD) remain controversial in treating pancreatic head cancer. We evaluated the oncologic benefit of LPD and compared the inflammatory score between LPD and open pancreaticoduodenectomy (OPD). METHODS: From January 2014 to March 2019, 61 patients with standard PD not combined with other organ resection were finally enrolled in this study. Among these patients, 27 underwent LPD and 34 underwent OPD (registered on 16 July 2019, and registration number is 2019-1411-001). RESULTS: The estimated blood loss (EBL) for the LPD group was less than that of the OPD group (P = 0.003). The operation time was similar, as was the incidence of complications such as postoperative fistula, delayed gastric emptying. Overall survival was not different between LPD and OPD (44.62 vs. 45.29 months, P = 0.223). However, a significant improvement in disease-free survival (DFS) was seen in the LPD group (34.19 vs. 23.27 months, P = 0.027). No statistically significant differences were found in terms of the postoperative change in inflammatory scores and differentiated white blood cell counts. CONCLUSIONS: LPD is not only safe and feasible in pancreatic head cancer patients but is associated with a reduced amount of EBL, favorable DFS.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherWiley Japan-
dc.relation.isPartOfJOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleComparing laparoscopic and open pancreaticoduodenectomy in patients with pancreatic head cancer: oncologic outcomes and inflammatory scores-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthorMunseok Choi-
dc.contributor.googleauthorHo Kyoung Hwang-
dc.contributor.googleauthorSeoung Yoon Rho-
dc.contributor.googleauthorWoo Jung Lee-
dc.contributor.googleauthorChang Moo Kang-
dc.identifier.doi10.1002/jhbp.697-
dc.contributor.localIdA00088-
dc.contributor.localIdA05469-
dc.contributor.localIdA02993-
dc.contributor.localIdA05885-
dc.contributor.localIdA04497-
dc.relation.journalcodeJ01440-
dc.identifier.eissn1868-6982-
dc.identifier.pmid31705719-
dc.identifier.urlhttps://onlinelibrary.wiley.com/doi/full/10.1002/jhbp.697-
dc.subject.keywordDisease-free survival-
dc.subject.keywordInflammation-
dc.subject.keywordLaparoscopy-
dc.subject.keywordPancreatic cancer-
dc.subject.keywordPancreaticoduodenectomy-
dc.contributor.alternativeNameKang, Chang Moo-
dc.contributor.affiliatedAuthor강창무-
dc.contributor.affiliatedAuthor노승윤-
dc.contributor.affiliatedAuthor이우정-
dc.contributor.affiliatedAuthor최문석-
dc.contributor.affiliatedAuthor황호경-
dc.citation.volume27-
dc.citation.number3-
dc.citation.startPage124-
dc.citation.endPage131-
dc.identifier.bibliographicCitationJOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES, Vol.27(3) : 124-131, 2020-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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