Cited 9 times in
Comparison of Biochemical Recurrence After Robot-assisted Laparoscopic Radical Prostatectomy with Volatile and Total Intravenous Anesthesia
DC Field | Value | Language |
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dc.contributor.author | 김나영 | - |
dc.contributor.author | 유영철 | - |
dc.contributor.author | 장원식 | - |
dc.contributor.author | 최영득 | - |
dc.date.accessioned | 2020-02-26T06:50:42Z | - |
dc.date.available | 2020-02-26T06:50:42Z | - |
dc.date.issued | 2020 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175310 | - |
dc.description.abstract | Aims: Recurrence after cancer surgery is a major concern in patients with cancer. Growing evidence from preclinical studies has revealed that various anesthetics can influence the immune system in different ways. The current study compared the long-term biochemical recurrence of prostate cancer after robot-assisted laparoscopic radical prostatectomy (RALP) in terms of selection of anesthetic agent between total intravenous anesthesia (TIVA) with propofol/remifentanil and volatile anesthetics (VA) with sevoflurane or desflurane/remifentanil. Methods: We followed up oncologic outcomes of patients who underwent RALP from two previous prospective randomized controlled trials, and the outcomes of those who received TIVA (n = 64) were compared with those who received VA (n = 64). The follow-up period lasted from November 2010 to March 2019. Results: Both TIVA and VA groups showed identical biochemical recurrence-free survivals at all-time points after RALP. The following predictive factors of prostate cancer recurrence were determined by Cox regression: colloid input [hazard ratio (HR)=1.002, 95% confidence interval (CI): 1.000-1.003; P = 0.011], initial prostate-specific antigen level (HR=1.025, 95% CI: 1.007-1.044; P = 0.006), and pathological tumor stage 3b (HR=4.217, 95% CI:1.207-14.735; P = 0.024), but not the anesthetic agent. Conclusions: Our findings demonstrate that both TIVA with propofol/remifentanil and VA with sevoflurane or desflurane/remifentanil have comparable effects on oncologic outcomes in patients undergoing RALP. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Ivyspring International Publisher | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Comparison of Biochemical Recurrence After Robot-assisted Laparoscopic Radical Prostatectomy with Volatile and Total Intravenous Anesthesia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Na Young Kim | - |
dc.contributor.googleauthor | Won Sik Jang | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.contributor.googleauthor | Jung Hwa Hong | - |
dc.contributor.googleauthor | Sewon Noh | - |
dc.contributor.googleauthor | Young-Chul Yoo | - |
dc.identifier.doi | 10.7150/ijms.40958 | - |
dc.contributor.localId | A00348 | - |
dc.contributor.localId | A02484 | - |
dc.contributor.localId | A05268 | - |
dc.contributor.localId | A04111 | - |
dc.relation.journalcode | J02917 | - |
dc.identifier.eissn | 1449-1907 | - |
dc.subject.keyword | Prostate cancer | - |
dc.subject.keyword | recurrence | - |
dc.subject.keyword | propofol | - |
dc.subject.keyword | volatile | - |
dc.subject.keyword | anesthesia | - |
dc.contributor.alternativeName | Kim, Na Young | - |
dc.contributor.affiliatedAuthor | 김나영 | - |
dc.contributor.affiliatedAuthor | 유영철 | - |
dc.contributor.affiliatedAuthor | 장원식 | - |
dc.contributor.affiliatedAuthor | 최영득 | - |
dc.citation.volume | 17 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 449 | - |
dc.citation.endPage | 456 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF MEDICAL SCIENCES, Vol.17(4) : 449-456, 2020 | - |
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