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Comparative efficacy of per-oral endoscopic myotomy and Heller myotomy in patients with achalasia: a meta-analysis
DC Field | Value | Language |
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dc.contributor.author | 정다현 | - |
dc.date.accessioned | 2020-02-26T06:36:13Z | - |
dc.date.available | 2020-02-26T06:36:13Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0016-5107 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/175215 | - |
dc.description.abstract | BACKGROUND AND AIMS: Although both per-oral endoscopic myotomy (POEM) and Heller myotomy (HM) have been used for the treatment of achalasia, the comparative efficacy of POEM and HM has yet to be fully evaluated. METHODS: We searched all relevant studies published up to September 2018 examining the comparative efficacy between POEM and HM. Study quality was assessed using the Newcastle-Ottawa scale. Meta-analyses for Eckardt scores, perioperative outcomes, and reflux-related outcomes were performed based on a random-effects model. RESULTS: Fifteen studies with a total of 1213 patients were evaluated. The follow-up duration ranged from 2 to 46.2 months and from 2 to 54.2 months in the POEM and HM groups, respectively. Postoperative Eckardt scores were lower (better) in the POEM group than in the HM group (pooled standardized mean difference [SMD], -0.58; 95% confidence interval [CI], -1.03 to -0.13). Length of myotomy was greater in the POEM group than in the HM group (pooled SMD, 0.63; 95% CI, 0.42-0.84). There was no difference in reflux symptoms and pathologic reflux on pH monitoring between the groups (pooled risk ratio [RR], 1.03; 95% CI, 0.61-1.73; and pooled RR, 1.22; 95% CI, 0.67-2.25, respectively). Erosive esophagitis on endoscopy tended to be less common in the HM group (pooled RR, 1.88; 95% CI, 0.98-3.62). CONCLUSION: Although long-term follow-up data are insufficient, the short-term efficacy of POEM was superior to that of HM. Erosive esophagitis tended to be more common in the POEM group; however, there was no difference in reflux symptoms and pathologic reflux on pH monitoring between the groups. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Mosby Yearbook | - |
dc.relation.isPartOf | GASTROINTESTINAL ENDOSCOPY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Comparative efficacy of per-oral endoscopic myotomy and Heller myotomy in patients with achalasia: a meta-analysis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Chan Hyuk Park | - |
dc.contributor.googleauthor | Da Hyun Jung | - |
dc.contributor.googleauthor | Do Hoon Kim | - |
dc.contributor.googleauthor | Chul-Hyun Lim | - |
dc.contributor.googleauthor | Hee Seok Moon | - |
dc.contributor.googleauthor | Jung Ho Park | - |
dc.contributor.googleauthor | Hye-Kyung Jung | - |
dc.contributor.googleauthor | Su Jin Hong | - |
dc.contributor.googleauthor | Suck Chei Choi | - |
dc.contributor.googleauthor | Oh Young Lee | - |
dc.identifier.doi | 10.1016/j.gie.2019.05.046 | - |
dc.contributor.localId | A03591 | - |
dc.relation.journalcode | J00920 | - |
dc.identifier.eissn | 1097-6779 | - |
dc.identifier.pmid | 31443929 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0016510719319388 | - |
dc.contributor.alternativeName | Jung, Da Hyun | - |
dc.contributor.affiliatedAuthor | 정다현 | - |
dc.citation.volume | 90 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 546 | - |
dc.citation.endPage | 558.e3 | - |
dc.identifier.bibliographicCitation | GASTROINTESTINAL ENDOSCOPY, Vol.90(4) : 546-558.e3, 2019 | - |
dc.identifier.rimsid | 63220 | - |
dc.type.rims | ART | - |
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