353 511

Cited 7 times in

Feasibility of hybrid TomoHelical- and TomoDirect-based volumetric gradient matching technique for total body irradiation

DC Field Value Language
dc.contributor.author김동욱-
dc.contributor.author김지훈-
dc.contributor.author김진성-
dc.contributor.author박광우-
dc.contributor.author윤홍인-
dc.contributor.author이호-
dc.contributor.author장경환-
dc.contributor.author홍채선-
dc.contributor.author한민철-
dc.date.accessioned2020-02-11T06:33:45Z-
dc.date.available2020-02-11T06:33:45Z-
dc.date.issued2019-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/174726-
dc.description.abstractBackground: Tomotherapy-based total body irradiation (TBI) is performed using the head-first position (HFP) and feet-first position (FFP) due to treatment length exceeding the 135 cm limit. To reduce the dosimetric variation at the match lines, we propose and verify a volumetric gradient matching technique (VGMT) by combining TomoHelical (TH) and TomoDirect (TD) modes. Methods: Two planning CT image sets were acquired with HFP and FFP using 15 × 55 × 18 cm3 of solid water phantom. Planning target volume (PTV) was divided into upper, lower, and gradient volumes. The junction comprised 2-cm thick five and seven gradient volumes (5-GVs and 7-GVs) to create a dose distribution with a gentle slope. TH-IMRT and TD-IMRT plans were generated with 5-GVs and 7-GVs. The setup error in the calculated dose was assessed by shifting dose distribution of the FFP plan by 5, 10, 15, and 20 mm in the longitudinal direction and comparing it with the original. Doses for 95% (D95) and 5% of the PTV (D5) were calculated for all simulated setup error plans. Absolute dose measurements were performed using an ionization chamber in the junction. Results: The TH&TD plan produced a linear gradient in junction volume, comparable to that of the TH&TH plan. D5 of the PTV was 110% of the prescribed dose when the FFP plan was shifted 0.7 cm and 1.2 cm in the superior direction for 5-GVs and 7-GVs. D95 of the PTV decreased to < 90% of the prescribed dose when the FF plan was shifted 1.1 cm and 1.3 cm in the inferior direction for 5-GVs and 7-GVs. The absolute measured dose showed a good correlation with the calculated dose in the gradient junction volume. The average percent difference (±SD) in all measured points was − 0.7 ± 1.6%, and the average dose variations between depths was − 0.18 ± 1.07%. Conclusion: VGMT can create a linear dose gradient across the junction area in both TH&TH and TH&TD and can minimize the dose sensitivity to longitudinal setup errors in tomotherapy-based TBI.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherBioMed Central-
dc.relation.isPartOfRADIATION ONCOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleFeasibility of hybrid TomoHelical- and TomoDirect-based volumetric gradient matching technique for total body irradiation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Radiation Oncology (방사선종양학교실)-
dc.contributor.googleauthorChae-Seon Hong-
dc.contributor.googleauthorMin-Joo Kim-
dc.contributor.googleauthorJihun Kim-
dc.contributor.googleauthorKyung Hwan Chang-
dc.contributor.googleauthorKwangwoo Park-
dc.contributor.googleauthorDong Wook Kim-
dc.contributor.googleauthorMin Cheol Han-
dc.contributor.googleauthorHong In Yoon-
dc.contributor.googleauthorJin Sung Kim-
dc.contributor.googleauthorHo Lee-
dc.identifier.doi10.1186/s13014-019-1435-5-
dc.contributor.localIdA05710-
dc.contributor.localIdA05823-
dc.contributor.localIdA04548-
dc.contributor.localIdA01432-
dc.contributor.localIdA04777-
dc.contributor.localIdA03323-
dc.contributor.localIdA05840-
dc.contributor.localIdA05846-
dc.relation.journalcodeJ02591-
dc.identifier.eissn1748-717X-
dc.subject.keywordTotal body irradiation-
dc.subject.keywordTomotherapy-
dc.subject.keywordTomoHelical-
dc.subject.keywordTomoDirect-
dc.subject.keywordField junction-
dc.subject.keywordDose gradient-
dc.subject.keywordSetup error-
dc.contributor.alternativeNameKim, Dong Wook-
dc.contributor.affiliatedAuthor김동욱-
dc.contributor.affiliatedAuthor김지훈-
dc.contributor.affiliatedAuthor김진성-
dc.contributor.affiliatedAuthor박광우-
dc.contributor.affiliatedAuthor윤홍인-
dc.contributor.affiliatedAuthor이호-
dc.contributor.affiliatedAuthor장경환-
dc.contributor.affiliatedAuthor홍채선-
dc.citation.volume14-
dc.citation.startPage233-
dc.identifier.bibliographicCitationRADIATION ONCOLOGY, Vol.14 : 233, 2019-
dc.identifier.rimsid63398-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiation Oncology (방사선종양학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.