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Population-Based Epidemiology of Pediatric Patients with Treated Tic Disorders from Real-World Evidence in Korea

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dc.contributor.author송동호-
dc.contributor.author천근아-
dc.date.accessioned2020-02-11T06:32:01Z-
dc.date.available2020-02-11T06:32:01Z-
dc.date.issued2019-
dc.identifier.issn1044-5463-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/174716-
dc.description.abstractObjectives: Although tic disorder (TD) is a common mental disorder in children and adolescents, epidemiological data based on real-world evidence (RWE) are insufficient. Using RWE, this study sought to examine the prevalence of treated TD, use of medical utilization, and use of prescription drugs among patients with TD with respect to TD type and comorbid psychiatric illness. Methods: We performed a retrospective cross-sectional study. Using the Korean Health Insurance Review and Assessment Service Pediatric Patient Sample data from 2009 to 2016, we analyzed 20,599 patients with TD (Korean Standard Classification of Diseases-6/7 code: F95.x) aged 2-19 years. Results: The annual average TD prevalence was 2.6/1000 population (95% confidence interval, 2.3-2.8/1000). Between 2009 and 2016, a slight increase in TD prevalence was observed from 1.9 to 2.9/1000 population. The TD prevalence rate in male patients was four times higher than that in female patients. Differences were observed in health care utilization and drug prescription types between patients with Tourette syndrome and chronic or transient TD. In addition, more than half of patients with TD had comorbid psychiatric disorders, and one-third of patients with TD had attention-deficit/hyperactivity disorder (ADHD). Patients with TD without comorbidities were frequently prescribed aripiprazole, while patients with TD and comorbid ADHD were frequently prescribed atomoxetine, methylphenidate, risperidone, and aripiprazole. Conclusion: This study described the epidemiological characteristics of TD based on recent RWE from Korea, and its findings can help establish future TD evidence-based clinical guidelines and related policies.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherMary Ann Liebert-
dc.relation.isPartOfJOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePopulation-Based Epidemiology of Pediatric Patients with Treated Tic Disorders from Real-World Evidence in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Psychiatry (정신과학교실)-
dc.contributor.googleauthorSeungjin Choi-
dc.contributor.googleauthorHankil Lee-
dc.contributor.googleauthorDong-Ho Song-
dc.contributor.googleauthorKeun-Ah Cheon-
dc.identifier.doi10.1089/cap.2019.0050-
dc.contributor.localIdA02018-
dc.contributor.localIdA04027-
dc.relation.journalcodeJ01310-
dc.identifier.eissn1557-8992-
dc.identifier.pmid31361509-
dc.identifier.urlhttps://www.liebertpub.com/doi/abs/10.1089/cap.2019.0050-
dc.subject.keywordKorea-
dc.subject.keywordadolescent-
dc.subject.keywordchild-
dc.subject.keywordcomorbidity-
dc.subject.keywordmedication-
dc.subject.keywordprevalence-
dc.subject.keywordtic disorders-
dc.contributor.alternativeNameSong, Dong Ho-
dc.contributor.affiliatedAuthor송동호-
dc.contributor.affiliatedAuthor천근아-
dc.citation.volume29-
dc.citation.number10-
dc.citation.startPage764-
dc.citation.endPage772-
dc.identifier.bibliographicCitationJOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY, Vol.29(10) : 764-772, 2019-
dc.identifier.rimsid64025-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers

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