Cited 6 times in
Risk factors of community-onset extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteraemia in South Korea using national health insurance claims data
DC Field | Value | Language |
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dc.contributor.author | 김도균 | - |
dc.contributor.author | 정석훈 | - |
dc.date.accessioned | 2020-02-11T06:22:34Z | - |
dc.date.available | 2020-02-11T06:22:34Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0924-8579 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174652 | - |
dc.description.abstract | BACKGROUND: Although it is essential to know the particular causes of antibiotic-resistant infections in the community, there is lack of evidence regarding risk factors for community-onset extended-spectrum β-lactamase-producing Klebsiella pneumoniae (ESBL-KP) bacteraemia in South Korea. As such, this study aimed to identify risk factors for community-onset ESBL-KP bacteraemia. METHODS: From May 2016 to April 2017, patients with community-onset KP bloodstream infection (BSI) (n = 408) from six sentinel hospitals participating in the Global Antimicrobial Surveillance System in South Korea were included in this study. Risk factors of ESBL-KP BSI were assessed. Polymerase chain reaction and sequencing to identify genes encoding ESBLs and multi-locus sequence typing were performed. RESULTS: Of the 408 patients with community-onset KP BSI, 70 (17%) had ESBL-KP BSI. Admission to a long-term-care hospital within the previous 3 months [odds ratio (OR) 5.7, 95% confidence interval (CI) 2.1-15.6; P = 0.001], previous use of trimethoprim/sulfamethoxazole (TMP/SMT; OR 11.5, 95% CI 2.7-48.6; P = 0.001) or extended-spectrum cephalosporin (OR 2.2, 95% CI 1.2-3.9; P = 0.01), and previous use of a urinary catheter (OR 2.3, 95% CI 1.1-4.5; P = 0.02) were independent risk factors for community-onset ESBL-KP BSI. ESBL-KP isolates most frequently carried the CTX-M-1 group ESBL (74%, n = 52). The most prevalent sequence type (ST) among the ESBL-KP isolates was ST48 (14%, n = 10). Among non-ESBL-KP isolates, ST23 was most prevalent (21%, n = 70). CONCLUSION: Previous admission to a long-term-care hospital, use of a urinary catheter and use of TMP/SMT or extended-spectrum cephalosporin within the previous 3 months were identified as risk factors for community-onset ESBL-KP BSI. Strict antibiotic stewardship and infection control measures are needed for long-term-care hospitals. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Science Publishers | - |
dc.relation.isPartOf | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Risk factors of community-onset extended-spectrum β-lactamase-producing Klebsiella pneumoniae bacteraemia in South Korea using national health insurance claims data | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | Yongseop Lee | - |
dc.contributor.googleauthor | Young Ah Kim | - |
dc.contributor.googleauthor | Dokyun Kim | - |
dc.contributor.googleauthor | Jong Hee Shin | - |
dc.contributor.googleauthor | Young Uh | - |
dc.contributor.googleauthor | Kyeong Seob Shin | - |
dc.contributor.googleauthor | Jeong Hwan Shin | - |
dc.contributor.googleauthor | Seok Hoon Jeong | - |
dc.contributor.googleauthor | Yoon Soo Park | - |
dc.identifier.doi | 10.1016/j.ijantimicag.2019.09.005 | - |
dc.contributor.localId | A04891 | - |
dc.contributor.localId | A01598 | - |
dc.contributor.localId | A03619 | - |
dc.relation.journalcode | J01088 | - |
dc.identifier.eissn | 1872-7913 | - |
dc.identifier.pmid | 31520781 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0924857919302481 | - |
dc.subject.keyword | Community-onset | - |
dc.subject.keyword | Extended-spectrum β-lactamase | - |
dc.subject.keyword | Klebsiella pneumoniae | - |
dc.subject.keyword | Risk factor | - |
dc.contributor.alternativeName | Kim, Dokyun | - |
dc.contributor.affiliatedAuthor | 김도균 | - |
dc.contributor.affiliatedAuthor | 정석훈 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 723 | - |
dc.citation.endPage | 727 | - |
dc.identifier.bibliographicCitation | INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, Vol.54(6) : 723-727, 2019 | - |
dc.identifier.rimsid | 63496 | - |
dc.type.rims | ART | - |
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