Cited 12 times in
Predicting variceal bleeding in patients with biliary atresia
DC Field | Value | Language |
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dc.contributor.author | 강윤구 | - |
dc.contributor.author | 고홍 | - |
dc.contributor.author | 김승 | - |
dc.contributor.author | 박소원 | - |
dc.contributor.author | 한석주 | - |
dc.date.accessioned | 2020-02-11T06:16:44Z | - |
dc.date.available | 2020-02-11T06:16:44Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0036-5521 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174616 | - |
dc.description.abstract | Background/aims: Variceal bleeding is the main cause of morbidity and mortality in children with portal hypertension and biliary atresia. The aim of this study is to predict high-risk varices by analyzing various clinical factors, thus improve prognosis of patients with biliary atresia.Methods: A total of 157 patients with biliary atresia who underwent Kasai portoentrostomy were enrolled in a single center. Clinical data including laboratory values, endoscopic findings and values of transient elastography (FibroScan®) were analyzed retrospectively.Results: The bleeding group and the non-bleeding group showed statistically significant differences in several variables; The FibroScan® value (HR 1.05, 95% CI (1.03-1.07), p < .01) was higher in the bleeding group. The bleeding group had values of lower albumin after 3 months of operation (HR 0.28, 95% CI (0.11-0.73), p = .01), higher bilirubin after 3 months of operation (total bilirubin: HR 1.18, 95% CI (1.04-1.33), p = .01), (direct bilirubin: HR 1.21, 95% CI (1.05-1.41), p = .01). Gastric varix (HR 4.10, 95% CI (1.62-10.36), p < .01) was more frequent in the bleeding group. And the presence of red sign was also predictive of bleeding. The FibroScan® cut-off value with the predictive power of bleeding was 31.5 kPa (HR 7.7, 95% CI (3.36-17.73), p < .01).Conclusions: Several clinical factors including high value of transient elastography (FibroScan®), gastric varix or red sign of endoscopy, and low albumin or high bilirubin values after 3 months of Kasai operation can be useful in predicting variceal bleeding in patients with biliary atresia. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Informa Healthcare | - |
dc.relation.isPartOf | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Predicting variceal bleeding in patients with biliary atresia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pediatrics (소아청소년과학교실) | - |
dc.contributor.googleauthor | Hanbyul Sohn | - |
dc.contributor.googleauthor | Sowon Park | - |
dc.contributor.googleauthor | Yunkoo Kang | - |
dc.contributor.googleauthor | Hong Koh | - |
dc.contributor.googleauthor | Seok Joo Han | - |
dc.contributor.googleauthor | Seung Kim | - |
dc.identifier.doi | 10.1080/00365521.2019.1683225 | - |
dc.contributor.localId | A05213 | - |
dc.contributor.localId | A00156 | - |
dc.contributor.localId | A00651 | - |
dc.contributor.localId | A05216 | - |
dc.contributor.localId | A04288 | - |
dc.relation.journalcode | J02632 | - |
dc.identifier.eissn | 1502-7708 | - |
dc.identifier.pmid | 31646915 | - |
dc.identifier.url | https://www.tandfonline.com/doi/full/10.1080/00365521.2019.1683225 | - |
dc.subject.keyword | Children | - |
dc.subject.keyword | Kasai portoenterostomy | - |
dc.subject.keyword | endoscopy | - |
dc.subject.keyword | transient elastrography | - |
dc.contributor.alternativeName | Kang, Yunkoo | - |
dc.contributor.affiliatedAuthor | 강윤구 | - |
dc.contributor.affiliatedAuthor | 고홍 | - |
dc.contributor.affiliatedAuthor | 김승 | - |
dc.contributor.affiliatedAuthor | 박소원 | - |
dc.contributor.affiliatedAuthor | 한석주 | - |
dc.citation.volume | 54 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1385 | - |
dc.citation.endPage | 1390 | - |
dc.identifier.bibliographicCitation | SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY, Vol.54(11) : 1385-1390, 2019 | - |
dc.identifier.rimsid | 63680 | - |
dc.type.rims | ART | - |
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