Cited 17 times in
The effect of small or diminutive adenomas at baseline colonoscopy on the risk of developing metachronous advanced colorectal neoplasia: KASID multicenter study
DC Field | Value | Language |
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dc.contributor.author | 박재준 | - |
dc.contributor.author | 이현정 | - |
dc.contributor.author | 천재영 | - |
dc.date.accessioned | 2020-02-11T02:20:32Z | - |
dc.date.available | 2020-02-11T02:20:32Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1590-8658 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174466 | - |
dc.description.abstract | BACKGROUND: The clinical significance of diminutive or small adenomas remains ill defined. AIMS: We evaluated the clinical impact of diminutive or small adenomas at baseline on the risk of developing metachronous advanced colorectal neoplasia (CRN). METHODS: This multicenter, retrospective cohort study included 2252 patients with 1 or more colorectal adenomas at baseline and subsequent follow-up colonoscopy. Baseline colonoscopy findings were classified into 5 groups: 1 or 2 tubular adenomas (TAs) (<10 mm); 3-10 diminutive TAs (≤5 mm); 3-10 TAs, including 1 or 2 small adenomas (6-10 mm); 3-10 TAs, including 3 or more small adenomas; and advanced adenoma. RESULTS: In multivariate analysis, after adjusting for possible confounding variables (age at baseline, sex, body mass index, smoking habits, family history of colorectal cancer, regular use of aspirin or NSAIDs, and adenoma location), 3-10 TAs including 3 or more small adenomas (hazard ratio [HR] = 2.36, p = 0.034) and advanced adenoma (HR = 2.14, p < 0.001) were independent predictors for the risk of developing metachronous advanced CRN. However, 3-10 diminutive TAs or 3-10 TAs, including 1 or 2 small adenomas, were not associated with this outcome. CONCLUSIONS: Multiplicity of diminutive TAs, without advanced lesions, showed no clinical significance for risk of developing metachronous advanced CRN. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | DIGESTIVE AND LIVER DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adenoma/classification | - |
dc.subject.MESH | Adenoma/diagnosis* | - |
dc.subject.MESH | Adenoma/pathology | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Aged, 80 and over | - |
dc.subject.MESH | Colonoscopy* | - |
dc.subject.MESH | Colorectal Neoplasms/classification | - |
dc.subject.MESH | Colorectal Neoplasms/diagnosis* | - |
dc.subject.MESH | Colorectal Neoplasms/pathology | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Longitudinal Studies | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Neoplasms, Second Primary/epidemiology* | - |
dc.subject.MESH | Neoplasms, Second Primary/pathology | - |
dc.subject.MESH | Practice Guidelines as Topic | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Young Adult | - |
dc.title | The effect of small or diminutive adenomas at baseline colonoscopy on the risk of developing metachronous advanced colorectal neoplasia: KASID multicenter study | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Chang Mo Moon | - |
dc.contributor.googleauthor | Sung-Ae Jung | - |
dc.contributor.googleauthor | Chang Soo Eun | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Geom Seog Seo | - |
dc.contributor.googleauthor | Jae Myung Cha | - |
dc.contributor.googleauthor | Sung Chul Park | - |
dc.contributor.googleauthor | Jaeyoung Chun | - |
dc.contributor.googleauthor | Hyun Jung Lee | - |
dc.contributor.googleauthor | Yunho Jung | - |
dc.contributor.googleauthor | Sun-Jin Boo | - |
dc.contributor.googleauthor | Jin Oh Kim | - |
dc.contributor.googleauthor | Young-Eun Joo | - |
dc.contributor.googleauthor | Dong Il Park | - |
dc.identifier.doi | 10.1016/j.dld.2018.04.001 | - |
dc.contributor.localId | A01636 | - |
dc.contributor.localId | A03295 | - |
dc.contributor.localId | A05701 | - |
dc.relation.journalcode | J00735 | - |
dc.identifier.eissn | 1878-3562 | - |
dc.identifier.pmid | 29730157 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1590865818306960 | - |
dc.subject.keyword | Diminutive adenoma | - |
dc.subject.keyword | Metachronous colorectal neoplasia | - |
dc.subject.keyword | Small adenoma | - |
dc.subject.keyword | Surveillance | - |
dc.contributor.alternativeName | Park, Jae Jun | - |
dc.contributor.affiliatedAuthor | 박재준 | - |
dc.contributor.affiliatedAuthor | 이현정 | - |
dc.contributor.affiliatedAuthor | 천재영 | - |
dc.citation.volume | 50 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 847 | - |
dc.citation.endPage | 852 | - |
dc.identifier.bibliographicCitation | DIGESTIVE AND LIVER DISEASE, Vol.50(8) : 847-852, 2018 | - |
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