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경막외 마취를 받은 제왕절개 환자의 통증관리시 Ketamine의 경막외강 투여시기에 따른 진통효과
DC Field | Value | Language |
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dc.contributor.author | 이윤우 | - |
dc.date.accessioned | 2020-01-23T05:35:51Z | - |
dc.date.available | 2020-01-23T05:35:51Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0302-5780 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174398 | - |
dc.description.abstract | BACKGROUND : The NMDA receptor mediates wind-up and long-term potentiation in the responses of cells to prolonged stimuli; thus we postulated that the induction and maintenance of sensitization would be affected by the timing of epidural ketamine administration under epidural anesthesia. METHODS : Sixty patients undergoing elective cesarian section were randomly and equally assigned to one of three groups. 20 ml of 2% lidocaine and 2 mg morphine with epinephrine was injected to all patients epidurally through an indwelling catheter inserted at the L2-3 interspace. Before surgical incision, the patients in group 1 were given 3 ml saline, while the patients in group 2 were given 30 mg ketamine. In group 3, patients were injected with 30 mg ketamine after peritoneal closure. An additional 2 mg morphine was injected into all patients 24 h after surgery. The analgesic effects were assessed and side effects were also evaluated. RESULTS : VAS of group 3 at 3 24 h was lower than in the group 1, and at 6 24 h it was lower than in the group 2. The number of patients using additional analgesics in group 3 was lower than in the other groups. The incidence of nausea and vomiting was higher in the group 1 than in the other groups, but dizzness was higher in the groups 2 and 3 than in the control group. CONCLUSIONS : Preoperative administration of epidural ketamine is less effective in reducing postoperative pain than when given after peritoneal closure, especially under epidural anesthesia with local anesthetics. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한마취과학회 | - |
dc.relation.isPartOf | Journal of Korean Society of Anesthesiologist (대한마취과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 경막외 마취를 받은 제왕절개 환자의 통증관리시 Ketamine의 경막외강 투여시기에 따른 진통효과 | - |
dc.title.alternative | The Effects of Preoperative or Postperitoneal Closure Epidural Ketamine on Epidural Anesthesia and Analgesia for Obstetric Patients | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | 홍정연 | - |
dc.contributor.googleauthor | 이윤우 | - |
dc.contributor.localId | A03022 | - |
dc.relation.journalcode | J01540 | - |
dc.subject.keyword | Analgesics | - |
dc.subject.keyword | ketamine | - |
dc.subject.keyword | morphine | - |
dc.subject.keyword | Pain | - |
dc.subject.keyword | postoperative | - |
dc.contributor.alternativeName | Lee, Youn Woo | - |
dc.contributor.affiliatedAuthor | 이윤우 | - |
dc.citation.volume | 37 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 276 | - |
dc.citation.endPage | 282 | - |
dc.identifier.bibliographicCitation | Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.37(2) : 276-282, 1999 | - |
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