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균혈증 환자에서 분리된 group B Streptococcus의 항원형과 항균제 감수성

Other Titles
 Group B Streptococcus Isolated from Bacteremic Patients: Serotypes and Antimicrobial Susceptibilities 
Authors
 신정원  ;  노경호  ;  이경원  ;  정윤섭 
Citation
 Korean Journal of Clinical Microbiology (대한임상미생물학회지), Vol.2(2) : 220-224, 1999 
Journal Title
 Korean Journal of Clinical Microbiology (대한임상미생물학회지) 
ISSN
 1229-0025 
Issue Date
1999
Keywords
Group B Streptococcus ; Serotype ; Antimicrobial susceptibility
Abstract
Group B Streptococcus (GBS, S. agalactiae) is known to be the leading cause of neonatal sepsis and meningitis and the infection has been increasingly noted in adults, particularly in those with underlying diseases. Penicillin G is the drug of choice for GBS infection. However, the MIC of penicillin for GBS is greater than that for S. pyogenes. Therefore some GBS infections may be difficult to be treated. However, in Korea, our knowledge on GBS infection is limited. We observed 7 cases of GBS bacteremia during 1993-1996 in a hospital, Of the 7 patients, 3 were less than one month of age with no known underlying disease and 4 were adults with liver cirrhosis or malignancy. One adult patient developed disseminated intravascular coagulopathy and expired. Among the GBS isolates, 4 were serotype Ⅲ and 3 were Ⅰb. All of the isolates were susceptible to ampicillin, teicoplanin and vancomycin, but most were intermediate or resistant to clindamycin, erythromycin or tetracycline. It is concluded that GBS also cause severe infections in adult with underlying diseases and the serotypes Ⅲ and Ⅰb may be more virulent than other serotypes. Early detection and antimicrobial susceptibility test of GBS from severe infection may be necessary for the proper treatment of the patients.
Files in This Item:
T199902590.pdf Download
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/174197
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