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비정상피종성 고환 생식세포종양의 위험 인자와 생존율에 대한 분석

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dc.contributor.author양승철-
dc.contributor.author정병하-
dc.contributor.author홍성준-
dc.date.accessioned2020-01-23T05:16:02Z-
dc.date.available2020-01-23T05:16:02Z-
dc.date.issued1999-
dc.identifier.issn0494-4747-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/174137-
dc.description.abstractPurpose : We reviewed clinical features and survival rates of nonseminomatous germ cell testicular tumors(NSGCTs) and analyzed pathological risk factors of relapse in stage 1 group under surveillance program. Materials and Methods : Forty one patients were treated for primary NSGCTs from February 1983 to April 1998. 20(48.8%) patients were stage Ⅰ and 19 of them were followed up under surveillance program after orchiectomy and 1 underwent orchiectomy and adjuvant therapy(RPLND and PVB chemotherapy). 11(26.8%) were stage Ⅱ and 10(24.4%) stage Ⅲ and all stage Ⅱ and Ⅲ patients underwent orchiectomy and adjuvant therapy. Statistical analysis with Fisher's exact test was performed to identify that pathological risk factors affected relapse rate. Results : Mean age at diagnosis was 26 year(range 16-47) and mean follow-up period was 58 month(range 5-163). According to histopathological types, embryonal carcinoma, teratoma, teratocarcinoma and mixed type represented 19.5%, 26.8%, 7.3% and 46.3%, respectively. Among 41 patients, 33 showed significant elevation of tumor markers at diagnosis. The 5-year survival rates of stage Ⅰ, Ⅱ and Ⅲ were 95%, 80% and 56%, respectively and overall 5-year survival rate was 82%. Among stage Ⅰ patients under surveillance program, there was statistically significant increase of relapse rate in the patients with pathological risk factors(presence of embryonal elements, local stage T2 or higher, presence of lymphovascular invasion) as compared to those without. Conclusions : In stage Ⅰ NSGCT patients, if there are pathological risk factors after orchiectomy, aggressive therapy such as early retroperitoneal lymph node dissection or chemotherapy is selectively needed.-
dc.description.statementOfResponsibilityprohibition-
dc.languageKorean-
dc.publisher대한비뇨기과학회-
dc.relation.isPartOfKorean Journal of Urology (대한비뇨기과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title비정상피종성 고환 생식세포종양의 위험 인자와 생존율에 대한 분석-
dc.title.alternativeClinical Experience of Nonseminomatous Germ Cell Testicular Tumor: Risk Factors and Survival Rate-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthor송희원-
dc.contributor.googleauthor정병하-
dc.contributor.googleauthor홍성준-
dc.contributor.googleauthor양승철-
dc.contributor.googleauthor이진무-
dc.contributor.localIdA02294-
dc.contributor.localIdA03607-
dc.contributor.localIdA04402-
dc.relation.journalcodeJ02135-
dc.subject.keywordNonseminomatous germ cell testicular tumor-
dc.subject.keywordRelapse-
dc.subject.keywordPathological risk factors-
dc.contributor.alternativeNameYang, Seung Choul-
dc.contributor.affiliatedAuthor양승철-
dc.contributor.affiliatedAuthor정병하-
dc.contributor.affiliatedAuthor홍성준-
dc.citation.volume40-
dc.citation.number4-
dc.citation.startPage453-
dc.citation.endPage7-
dc.identifier.bibliographicCitationKorean Journal of Urology (대한비뇨기과학회지), Vol.40(4) : 453-7, 1999-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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