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자궁경부암 환자에서 Bcl-2 gene과 Cd-44 molecules의 발현의 임상적 의의 및 예후인자와의 상관관계
DC Field | Value | Language |
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dc.contributor.author | 김영태 | - |
dc.contributor.author | 이병석 | - |
dc.contributor.author | 조남훈 | - |
dc.date.accessioned | 2020-01-23T05:08:27Z | - |
dc.date.available | 2020-01-23T05:08:27Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0494-4755 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/174031 | - |
dc.description.abstract | OBJECTIVE: The study was designed to investigate the expression of Bcl-2 and CD-44 molecules in cervical cancer and compare the results with known clinical prognostic factors, and lastly to define the roles of Bcl-2 and CD-44 molecules in tumorigenesis and metastasis of cervical cancer.0aMETHODS: A total of 85 patients were enrolled in this study and retrospective analysis of prognostic factors were compared with immunohistochemical staining of Bcl-2 and CD-44. RESULTS: The expression of Bcl-2 was relatively even when we compared with stage, cell types, grade and lymph node metastasis. And the CD-44 spliced variant form V6 expression was significantly strong in higher stage and positive lymph node metastasis but cell types and grade of tumor does not correlated with status of CD-44 expression. 0aCONCLUSION: Bcl-2 expression in cervical cancer does not correlate with clinical prognostic factors, but CD-44 spliced variant V6 form does correlated with poor prognostic factors. CD-44 may play a role in the process of the tumor metastasis and poor prognosis. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | Korean | - |
dc.publisher | 대한산부인과학회 | - |
dc.relation.isPartOf | Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 자궁경부암 환자에서 Bcl-2 gene과 Cd-44 molecules의 발현의 임상적 의의 및 예후인자와의 상관관계 | - |
dc.title.alternative | The Clinical Significance of Expression of Bcl-2 and CD-44 molecules in Cervical Cancer and Its Correlation with Known Prognostic Factors | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Obstetrics and Gynecology (산부인과학교실) | - |
dc.contributor.googleauthor | 김동규 | - |
dc.contributor.googleauthor | 정현용 | - |
dc.contributor.googleauthor | 김영태 | - |
dc.contributor.googleauthor | 이병석 | - |
dc.contributor.googleauthor | 서경 | - |
dc.contributor.googleauthor | 이윤호 | - |
dc.contributor.googleauthor | 이국 | - |
dc.contributor.googleauthor | 김재욱 | - |
dc.contributor.googleauthor | 조남훈 | - |
dc.contributor.localId | A00729 | - |
dc.contributor.localId | A02795 | - |
dc.contributor.localId | A03812 | - |
dc.relation.journalcode | J02075 | - |
dc.identifier.url | http://kiss.kstudy.com/thesis/thesis-view.asp?key=1857574 | - |
dc.subject.keyword | Bcl-2 gene | - |
dc.subject.keyword | CD-44 molecules | - |
dc.subject.keyword | spliced variant form V6 | - |
dc.subject.keyword | cervical cancer | - |
dc.subject.keyword | 자궁경부암 | - |
dc.subject.keyword | CD-44분자 | - |
dc.contributor.alternativeName | Kim, Young Tae | - |
dc.contributor.affiliatedAuthor | 김영태 | - |
dc.contributor.affiliatedAuthor | 이병석 | - |
dc.contributor.affiliatedAuthor | 조남훈 | - |
dc.citation.volume | 42 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 2531 | - |
dc.citation.endPage | 2535 | - |
dc.identifier.bibliographicCitation | Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.42(11) : 2531-2535, 1999 | - |
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