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Clonidine과 meperidine의 마취후 전율에 대한 약물학적 예방효과: 메타분석 (meta-analysis)
DC Field | Value | Language |
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dc.contributor.author | 김원옥 | - |
dc.date.accessioned | 2020-01-07T08:43:20Z | - |
dc.date.available | 2020-01-07T08:43:20Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 2005-6419 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/173788 | - |
dc.description.abstract | BACKGROUND : Post-operative shivering is one of the potential complications for any surgical patient. Its incidence varies from 5% to 65%, and many preventive and treatment modalities have been reported. For the effective prevention of post-anesthetic shivering by using intravenous clonidine or meperidine, randomized controlled studies were reviewed. The overall incidence of shivering after clonidine or meperidine administration, and the anti-shivering effect of clonidine and meperidine were evaluated. METHODS : DATA SOURCES: Medline search from 1978 to March 1998. DATA SELECTION: We selected studies that had investigated the preventive anti-shivering effect of intravenous clonidine or meperidine by randomized controlled trials. Ten clinical trials were evaluated. RESULTS : The pooled odd ratio of the patients who received clonidine was 0.32 (95% confidence interval, 0.22~0.47) and it seemed to be effective. But these studies showed little evidence of significant homogeneity (P=0.01). In the subgroup analysis, the pooled odd ratio of group A (early administration or intra-operative infusion group) was 0.47 (95% CI 0.31~0.72) evidenced effectiveness but failed to prove homogeneity (P=0.047). But group B (the late intra-operative administration group) had a pooled odd ratio of 0.10 (95% CI 0.05~0.22) and showed homogeneity (P=0.98). In meperidine trials, the pooled odd ratio was 0.20 (95% CI 0.07~0.55). CONCLUSION : We present quantitative evidence based on a meta-analysis of pooled effect size from randomized trials that clonidine is more beneficial for the prevention of post-anesthetic shivering and more effective than meperidine when it is administrated during later period of surgery. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한마취과학회 | - |
dc.relation.isPartOf | Korean Journal Of Anesthesiology (대한마취과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Clonidine과 meperidine의 마취후 전율에 대한 약물학적 예방효과: 메타분석 (meta-analysis) | - |
dc.title.alternative | Pharmacological Prevention of Post-Anesthetic Shivering: Clonidine Vs Meperidine: A Meta-Analysis of Randomized-Controlled Trials | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | 민상기 | - |
dc.contributor.googleauthor | 김원옥 | - |
dc.contributor.googleauthor | 남용택 | - |
dc.contributor.googleauthor | 한상건 | - |
dc.contributor.googleauthor | 이성중 | - |
dc.contributor.googleauthor | 이영석 | - |
dc.identifier.doi | 10.4097/kjae.1999.37.1.63 | - |
dc.contributor.localId | A00766 | - |
dc.relation.journalcode | J03189 | - |
dc.identifier.eissn | 2005-7563 | - |
dc.subject.keyword | Analgesics, meperidine | - |
dc.subject.keyword | Statistics, meta-analysis | - |
dc.subject.keyword | Sympathetic nervous system, clonidine | - |
dc.subject.keyword | Temperature, shivering, postanesthetic | - |
dc.contributor.alternativeName | Kim, Won Oak | - |
dc.contributor.affiliatedAuthor | 김원옥 | - |
dc.citation.volume | 37 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 63 | - |
dc.citation.endPage | 72 | - |
dc.identifier.bibliographicCitation | Korean Journal Of Anesthesiology (대한마취과학회지), Vol.37(1) : 63-72, 1999 | - |
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