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Cited 2 times in

Triglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults

DC FieldValueLanguage
dc.contributor.author강신애-
dc.contributor.author김정혜-
dc.contributor.author남지선-
dc.contributor.author박가희-
dc.contributor.author박종숙-
dc.contributor.author백수정-
dc.contributor.author안철우-
dc.date.accessioned2019-12-18T01:16:50Z-
dc.date.available2019-12-18T01:16:50Z-
dc.date.issued2019-
dc.identifier.issn2093-596X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173452-
dc.description.abstractBACKGROUND: Recently, the triglyceride glucose (TyG) index has been considered a surrogate marker of insulin resistance which is a well-known pathogenic factor in nonalcoholic fatty liver disease (NAFLD). However, few studies have investigated the relationship between the TyG index and NAFLD. Thus, we investigated the relationship between the TyG index and NAFLD and the effectiveness of the TyG index compared with the homeostasis model assessment of insulin resistance (HOMA-IR) in identifying NAFLD in Korean adults. METHODS: Participants of 4,986 who underwent ultrasonography in a health promotion center were enrolled. The TyG index was calculated as ln [fasting triglycerides (mg/dL)×fasting glucose (mg/dL)/2], and HOMA-IR was estimated. NAFLD was diagnosed by ultrasonography. RESULTS: Significant differences were observed in metabolic parameters among the quartiles of the TyG index. The prevalence of NAFLD significantly increased with increment in the TyG index. After adjusting for multiple risk factors, a logistic regression analysis was performed. When the highest and lowest quartiles of the TyG index and HOMA-IR were compared, the odds ratios for the prevalence of NAFLD were 2.94 and 1.93 (95% confidence interval, 2.32 to 3.72 and 1.43 to 2.61; both P for trend <0.01), respectively. According to the receiver operating characteristic analysis, the TyG index was superior to HOMA-IR in predicting NAFLD. CONCLUSION: The TyG index and prevalence of NAFLD were significantly related and the TyG index was superior to HOMA-IR in predicting NAFLD in Korean adults.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Endocrine Society-
dc.relation.isPartOfEndocrinology and Metabolism (대한내분비학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleTriglyceride Glucose Index Is Superior to the Homeostasis Model Assessment of Insulin Resistance for Predicting Nonalcoholic Fatty Liver Disease in Korean Adults-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorSang Bae Lee-
dc.contributor.googleauthorMin Kyung Kim-
dc.contributor.googleauthorShinae Kang-
dc.contributor.googleauthorKahui Park-
dc.contributor.googleauthorJung Hye Kim-
dc.contributor.googleauthorSu Jung Baik-
dc.contributor.googleauthorJi Sun Nam-
dc.contributor.googleauthorChul Woo Ahn-
dc.contributor.googleauthorJong Suk Park-
dc.identifier.doi10.3803/EnM.2019.34.2.179-
dc.contributor.localIdA00052-
dc.contributor.localIdA05752-
dc.contributor.localIdA05752-
dc.contributor.localIdA01268-
dc.contributor.localIdA01268-
dc.contributor.localIdA05757-
dc.contributor.localIdA05757-
dc.contributor.localIdA01660-
dc.contributor.localIdA01660-
dc.contributor.localIdA04580-
dc.contributor.localIdA04580-
dc.contributor.localIdA02270-
dc.contributor.localIdA02270-
dc.relation.journalcodeJ00773-
dc.identifier.eissn2093-5978-
dc.identifier.pmid31257745-
dc.subject.keywordInsulin resistance-
dc.subject.keywordNon-alcoholic fatty liver disease-
dc.subject.keywordTriglyceride glucose index-
dc.contributor.alternativeNameKang, Shin Ae-
dc.contributor.affiliatedAuthor강신애-
dc.contributor.affiliatedAuthor김정혜-
dc.contributor.affiliatedAuthor김정혜-
dc.contributor.affiliatedAuthor남지선-
dc.contributor.affiliatedAuthor남지선-
dc.contributor.affiliatedAuthor박가희-
dc.contributor.affiliatedAuthor박가희-
dc.contributor.affiliatedAuthor박종숙-
dc.contributor.affiliatedAuthor박종숙-
dc.contributor.affiliatedAuthor백수정-
dc.contributor.affiliatedAuthor백수정-
dc.contributor.affiliatedAuthor안철우-
dc.contributor.affiliatedAuthor안철우-
dc.citation.volume34-
dc.citation.number2-
dc.citation.startPage179-
dc.citation.endPage186-
dc.identifier.bibliographicCitationEndocrinology and Metabolism (대한내분비학회지), Vol.34(2) : 179-186, 2019-
Appears in Collections:
7. Others (기타) > Gangnam Severance Hospital (강남세브란스병원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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