Cited 4 times in
Different prognosis of patients with esophageal carcinoma with M1a and regional node involvement
DC Field | Value | Language |
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dc.contributor.author | 김준원 | - |
dc.contributor.author | 김지현 | - |
dc.contributor.author | 박효진 | - |
dc.contributor.author | 윤영훈 | - |
dc.contributor.author | 이익재 | - |
dc.contributor.author | 이창걸 | - |
dc.contributor.author | 정다현 | - |
dc.contributor.author | 조연아 | - |
dc.contributor.author | 박재준 | - |
dc.date.accessioned | 2019-12-18T01:11:33Z | - |
dc.date.available | 2019-12-18T01:11:33Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1590-8658 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/173411 | - |
dc.description.abstract | BACKGROUND AND PURPOSE: Based on the 6th edition of the American Joint Commission on Cancer (AJCC) staging system for esophageal squamous cell carcinoma (ESCC), M1a node involvement was classified as regional node involvement in the revised 7th/8th edition. However, the clinical significance of M1a node involvement is unclear. Thus, we analyzed the prognostic value of M1a node involvement in patients with ESCC after definitive concurrent chemoradiotherapy (CCRT). MATERIALS AND METHODS: In total, 188 patients with ESCC had M0 disease according to the 7th/8th edition AJCC. We reclassified 31 (16.5%) of these patients as having M1a disease according to the 6th edition. After definitive CCRT, we compared baseline characteristics between the two groups and analyzed the rates of responders and recurrence. Finally, we compared prognoses according to overall survival (OS), disease-specific OS, and disease-free survival (DFS). RESULTS: Among 31 patients reclassified to have M1a disease, 21 (67.7%) had supraclavicular lymph node metastasis and 10 (32.3%) had celiac lymph node metastasis. The number of responders was significantly lower for M1a disease based on univariate (p = 0.004) and multivariate (p = 0.011) analyses. Significantly lower survival rates were observed in individuals with M1a disease (median OS, 16.4 vs. 42.7 months; 5-year OS, 10.8% vs. 41.2%). CONCLUSIONS: M1a node involvement should be differentiated from regional node involvement. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | DIGESTIVE AND LIVER DISEASE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Different prognosis of patients with esophageal carcinoma with M1a and regional node involvement | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Radiation Oncology (방사선종양학교실) | - |
dc.contributor.googleauthor | Tae Ryong Chung | - |
dc.contributor.googleauthor | Jie-Hyun Kim | - |
dc.contributor.googleauthor | Ik Jae Lee | - |
dc.contributor.googleauthor | Yeona Cho | - |
dc.contributor.googleauthor | Jun Won Kim | - |
dc.contributor.googleauthor | Chang Geol Lee | - |
dc.contributor.googleauthor | Da Hyun Jung | - |
dc.contributor.googleauthor | Jae Jun Park | - |
dc.contributor.googleauthor | Young Hoon Youn | - |
dc.contributor.googleauthor | Hyojin Park | - |
dc.identifier.doi | 10.1016/j.dld.2019.05.014 | - |
dc.contributor.localId | A00958 | - |
dc.contributor.localId | A00996 | - |
dc.contributor.localId | A01774 | - |
dc.contributor.localId | A02583 | - |
dc.contributor.localId | A03055 | - |
dc.contributor.localId | A03240 | - |
dc.contributor.localId | A03591 | - |
dc.contributor.localId | A04680 | - |
dc.relation.journalcode | J00735 | - |
dc.identifier.eissn | 1878-3562 | - |
dc.identifier.pmid | 31175014 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S1590865819305936 | - |
dc.subject.keyword | Definitive concurrent chemoradiotherapy | - |
dc.subject.keyword | Esophageal squamous cell carcinoma | - |
dc.subject.keyword | M1a node involvement | - |
dc.contributor.alternativeName | Kim, Jun Won | - |
dc.contributor.affiliatedAuthor | 김준원 | - |
dc.contributor.affiliatedAuthor | 김지현 | - |
dc.contributor.affiliatedAuthor | 박효진 | - |
dc.contributor.affiliatedAuthor | 윤영훈 | - |
dc.contributor.affiliatedAuthor | 이익재 | - |
dc.contributor.affiliatedAuthor | 이창걸 | - |
dc.contributor.affiliatedAuthor | 정다현 | - |
dc.contributor.affiliatedAuthor | 조연아 | - |
dc.citation.volume | 51 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1610 | - |
dc.citation.endPage | 1616 | - |
dc.identifier.bibliographicCitation | DIGESTIVE AND LIVER DISEASE, Vol.51(11) : 1610-1616, 2019 | - |
dc.identifier.rimsid | 63638 | - |
dc.type.rims | ART | - |
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