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The association of family history of prostate cancer with the diagnosis of clinically significant prostate cancer in Korean population

DC Field Value Language
dc.contributor.author구교철-
dc.contributor.author박지수-
dc.contributor.author이광석-
dc.contributor.author정병하-
dc.date.accessioned2019-12-18T01:09:41Z-
dc.date.available2019-12-18T01:09:41Z-
dc.date.issued2019-
dc.identifier.issn2466-0493-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173395-
dc.description.abstractPurpose: The impact of family history on the diagnosis of the prostate cancer among Asian population remains controversial. We evaluated whether a positive family history of the prostate cancer in Korean men is associated with the diagnosis and aggressiveness of the prostate cancer. Materials and Methods: Patients who underwent a transrectal ultrasound-guided prostate biopsy from March 2015 to September 2017 were evaluated. Information on family history was obtained via a self-administered questionnaire. The presence of prostate cancer and clinically significant prostate cancer (Gleason score ≥7) was evaluated according to the presence of a family history. Results: Of 602 patients (median age, 68.3 years; median prostate-specific antigen level, 6.28 ng/mL), 41 (6.8%) patients had a family history of prostate cancer. Family history was a significant factor for detecting prostate cancer (odds ratio [OR], 2.99; 95% confidence interval [CI], 1.330-6.704; p=0.008). In multivariate analysis for predicting clinically significant prostate cancer, family history was a significant predictor (OR, 6.32; 95% CI; 2.790-14.298; p<0.001). Conclusions: A family history of prostate cancer in Korean men was a significant factor for predicting prostate cancer. Moreover, significant differences in the aggressive features of the disease were identified between patients with and without a family history.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Urological Association-
dc.relation.isPartOfINVESTIGATIVE AND CLINICAL UROLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleThe association of family history of prostate cancer with the diagnosis of clinically significant prostate cancer in Korean population-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorJee Soo Park-
dc.contributor.googleauthorKyo Chul Koo-
dc.contributor.googleauthorByung Ha Chung-
dc.contributor.googleauthorKwang Suk Lee-
dc.identifier.doi10.4111/icu.2019.60.6.442-
dc.contributor.localIdA00188-
dc.contributor.localIdA05336-
dc.contributor.localIdA02668-
dc.contributor.localIdA03607-
dc.relation.journalcodeJ01185-
dc.identifier.eissn2466-054X-
dc.identifier.pmid31692911-
dc.subject.keywordBiopsy-
dc.subject.keywordHistory-
dc.subject.keywordProstatic neoplasms-
dc.contributor.alternativeNameKoo, Kyo Chul-
dc.contributor.affiliatedAuthor구교철-
dc.contributor.affiliatedAuthor박지수-
dc.contributor.affiliatedAuthor이광석-
dc.contributor.affiliatedAuthor정병하-
dc.citation.volume60-
dc.citation.number6-
dc.citation.startPage442-
dc.citation.endPage446-
dc.identifier.bibliographicCitationINVESTIGATIVE AND CLINICAL UROLOGY, Vol.60(6) : 442-446, 2019-
dc.identifier.rimsid63626-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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