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Epidermal Lipids and Proteins, the Two Components of Skin Barrier

Authors
 Seong Hoon Seo  ;  Sang Eun Lee 
Citation
 Journal of Skin Barrier Research (한국피부장벽학회지), Vol.21(1) : 5-9, 2019 
Journal Title
Journal of Skin Barrier Research(한국피부장벽학회지)
ISSN
 1229-4934 
Issue Date
2019
Keywords
Barrier ; Epidermis ; Lipids ; Proteins
Abstract
Epidermis has protective barrier functions between the organism and the environment. The permeability barrier localized primarily in the stratum corneum (SC) and consists of protein-enriched cells (corneocytes with cornified envelope and cytoskeletal elements, corneodesmosomes) and lipid-enriched intercellular matrix. Recently, it has been suggested that the skin barrier function has three elements including the SC as air-liquid barrier, tight junctions as liquid-liquid barrier and the Langerhans cell network as immunologic barrier. In this review article, we summarize the epidermal lipids and proteins and their correlation with skin barrier structure and function.
Full Text
http://kiss.kstudy.com/thesis/thesis-view.asp?key=3696726
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Seo, Seong Hoon(서성훈)
Lee, Sang Eun(이상은) ORCID logo https://orcid.org/0000-0003-4720-9955
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/173357
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