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Application of Sepsis-3 Criteria to Korean Patients with Critical Illnesses

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dc.contributor.author나성원-
dc.date.accessioned2019-12-18T01:02:33Z-
dc.date.available2019-12-18T01:02:33Z-
dc.date.issued2019-
dc.identifier.issn2586-6052-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/173337-
dc.description.abstractBackground: The 2016 Society of Critical Care Medicine (SCCM)/European Society of Intensive Care Medicine (ESICM) task force for Sepsis-3 devised new definitions for sepsis, sepsis with organ dysfunction and septic shock. Although Sepsis-3 was data-driven, evidence-based approach, East Asian descents comprised minor portions of the project population. Methods: We selected Korean participants from the fever and antipyretics in critically ill patients evaluation (FACE) study, a joint study between Korea and Japan. We calculated the concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria and evaluated mortality rates of sepsis, sepsis with organ dysfunction, and septic shock by Sepsis-3 criteria using the selected data. Results: Korean participants of the FACE study were 913 (383 with sepsis and 530 without sepsis by Sepsis-2 criteria). The concordance rate for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria was 55.4%. The intensive care unit (ICU) and 28-day mortality rates of sepsis, sepsis with organ dysfunction, and septic shock patients according to Sepsis-3 criteria were 26.2% and 31.0%, 27.5% and 32.5%, and 40.8% and 43.4%, respectively. The quick Sequential Organ Failure Assessment (qSOFA) was inferior not only to SOFA but also to systemic inflammatory response syndrome (SIRS) for predicting ICU and 28-day mortality. Conclusions: The concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria were low. Mortality rate for septic shock in Koreans was consistent with estimates made by the 2016 SCCM/ESICM task force. SOFA and SIRS were better than qSOFA for predicting ICU and 28-day mortality in Korean ICU patients.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherKorean Society of Critical Care Medicine-
dc.relation.isPartOfACUTE AND CRITICAL CARE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleApplication of Sepsis-3 Criteria to Korean Patients with Critical Illnesses-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Anesthesiology and Pain Medicine (마취통증의학교실)-
dc.contributor.googleauthorJae Yeol Kim-
dc.contributor.googleauthorHwan Il Kim-
dc.contributor.googleauthorGee Young Suh-
dc.contributor.googleauthorSang Won Yoon-
dc.contributor.googleauthorTae-Yop Kim-
dc.contributor.googleauthorSang Haak Lee-
dc.contributor.googleauthorJae Young Moon-
dc.contributor.googleauthorJae-Young Kwon-
dc.contributor.googleauthorSungwon Na-
dc.contributor.googleauthorHo Geol Ryu-
dc.contributor.googleauthorJisook Park-
dc.contributor.googleauthorYounsuck Koh-
dc.identifier.doi10.4266/acc.2018.00318-
dc.contributor.localIdA01232-
dc.relation.journalcodeJ03501-
dc.identifier.eissn2586-6060-
dc.identifier.pmid31723902-
dc.subject.keywordSepsis-
dc.subject.keywordSepsis-3-
dc.subject.keywordintensive care units-
dc.subject.keywordorgan dysfunction-
dc.subject.keywordseptic shock-
dc.contributor.alternativeNameNa, Sung Won-
dc.contributor.affiliatedAuthor나성원-
dc.citation.volume34-
dc.citation.number1-
dc.citation.startPage30-
dc.citation.endPage37-
dc.identifier.bibliographicCitationACUTE AND CRITICAL CARE, Vol.34(1) : 30-37, 2019-
dc.identifier.rimsid64300-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers

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