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Application of Sepsis-3 Criteria to Korean Patients with Critical Illnesses
DC Field | Value | Language |
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dc.contributor.author | 나성원 | - |
dc.date.accessioned | 2019-12-18T01:02:33Z | - |
dc.date.available | 2019-12-18T01:02:33Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 2586-6052 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/173337 | - |
dc.description.abstract | Background: The 2016 Society of Critical Care Medicine (SCCM)/European Society of Intensive Care Medicine (ESICM) task force for Sepsis-3 devised new definitions for sepsis, sepsis with organ dysfunction and septic shock. Although Sepsis-3 was data-driven, evidence-based approach, East Asian descents comprised minor portions of the project population. Methods: We selected Korean participants from the fever and antipyretics in critically ill patients evaluation (FACE) study, a joint study between Korea and Japan. We calculated the concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria and evaluated mortality rates of sepsis, sepsis with organ dysfunction, and septic shock by Sepsis-3 criteria using the selected data. Results: Korean participants of the FACE study were 913 (383 with sepsis and 530 without sepsis by Sepsis-2 criteria). The concordance rate for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria was 55.4%. The intensive care unit (ICU) and 28-day mortality rates of sepsis, sepsis with organ dysfunction, and septic shock patients according to Sepsis-3 criteria were 26.2% and 31.0%, 27.5% and 32.5%, and 40.8% and 43.4%, respectively. The quick Sequential Organ Failure Assessment (qSOFA) was inferior not only to SOFA but also to systemic inflammatory response syndrome (SIRS) for predicting ICU and 28-day mortality. Conclusions: The concordance rates for sepsis diagnosis between Sepsis-2 and Sepsis-3 criteria were low. Mortality rate for septic shock in Koreans was consistent with estimates made by the 2016 SCCM/ESICM task force. SOFA and SIRS were better than qSOFA for predicting ICU and 28-day mortality in Korean ICU patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Korean Society of Critical Care Medicine | - |
dc.relation.isPartOf | ACUTE AND CRITICAL CARE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Application of Sepsis-3 Criteria to Korean Patients with Critical Illnesses | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) | - |
dc.contributor.googleauthor | Jae Yeol Kim | - |
dc.contributor.googleauthor | Hwan Il Kim | - |
dc.contributor.googleauthor | Gee Young Suh | - |
dc.contributor.googleauthor | Sang Won Yoon | - |
dc.contributor.googleauthor | Tae-Yop Kim | - |
dc.contributor.googleauthor | Sang Haak Lee | - |
dc.contributor.googleauthor | Jae Young Moon | - |
dc.contributor.googleauthor | Jae-Young Kwon | - |
dc.contributor.googleauthor | Sungwon Na | - |
dc.contributor.googleauthor | Ho Geol Ryu | - |
dc.contributor.googleauthor | Jisook Park | - |
dc.contributor.googleauthor | Younsuck Koh | - |
dc.identifier.doi | 10.4266/acc.2018.00318 | - |
dc.contributor.localId | A01232 | - |
dc.relation.journalcode | J03501 | - |
dc.identifier.eissn | 2586-6060 | - |
dc.identifier.pmid | 31723902 | - |
dc.subject.keyword | Sepsis | - |
dc.subject.keyword | Sepsis-3 | - |
dc.subject.keyword | intensive care units | - |
dc.subject.keyword | organ dysfunction | - |
dc.subject.keyword | septic shock | - |
dc.contributor.alternativeName | Na, Sung Won | - |
dc.contributor.affiliatedAuthor | 나성원 | - |
dc.citation.volume | 34 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 30 | - |
dc.citation.endPage | 37 | - |
dc.identifier.bibliographicCitation | ACUTE AND CRITICAL CARE, Vol.34(1) : 30-37, 2019 | - |
dc.identifier.rimsid | 64300 | - |
dc.type.rims | ART | - |
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