Cited 34 times in
Long-Term Mortality and Prognostic Factors in Aspiration Pneumonia
DC Field | Value | Language |
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dc.contributor.author | 이수환 | - |
dc.date.accessioned | 2019-12-18T00:40:14Z | - |
dc.date.available | 2019-12-18T00:40:14Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1525-8610 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/173165 | - |
dc.description.abstract | OBJECTIVES: Aspiration pneumonia is a leading cause of death among older patients; however, little is known about the long-term mortality in aspiration pneumonia. The purpose of this study was to evaluate long-term mortality and its associated factors in patients with aspiration pneumonia. DESIGN: Retrospective cohort study. SETTING AND PARTICIPANTS: In total, 550 patients with aspiration pneumonia (median age: 78.0 years, 66.4% male) with compatible clinical symptoms and chest computed tomography images were enrolled at a single tertiary center from 2006 to 2016. MEASURES: The 1-, 3-, and 5-year mortality rates were evaluated for all patients. The prognostic factors for 1-year and 5-year mortality were also evaluated using Cox proportional hazard models. RESULTS: A total of 441 (80.2%) patients died during a median follow-up of 50.7 weeks. The 1-, 3-, and 5-year mortality rates were 49.0%, 67.1%, and 76.9%, respectively. Multivariate analysis identified 5 risk factors for 1-year mortality of male sex [hazard ratio (HR) 1.533, P = .003], low body mass index (HR 0.934, P = .002), hypoalbuminemia, anemia (0.973, P = .032), and mechanical ventilation (HR 2.052, P < .001), which were also independent prognostic factors for 5-year mortality. During the follow-up period, 133 (24.2%) patients experienced recurrent aspiration pneumonia. However, Kaplan-Meier analysis showed no significant differences in survival curves between patients with single and recurrent aspiration pneumonia (P = .371). CONCLUSIONS/IMPLICATIONS: Long-term prognosis of aspiration pneumonia was poor as a result of underlying morbidity instead of the aspiration pneumonia itself. Our findings suggest that prognostic indices for patients with aspiration pneumonia including the patient's underlying conditions should be devised. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier | - |
dc.relation.isPartOf | JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Long-Term Mortality and Prognostic Factors in Aspiration Pneumonia | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Hee-Young Yoon | - |
dc.contributor.googleauthor | Sung Shine Shim | - |
dc.contributor.googleauthor | Soo Jung Kim | - |
dc.contributor.googleauthor | Jin Hwa Lee | - |
dc.contributor.googleauthor | Jung Hyun Chang | - |
dc.contributor.googleauthor | Su Hwan Lee | - |
dc.contributor.googleauthor | Yon Ju Ryu | - |
dc.identifier.doi | 10.1016/j.jamda.2019.03.029 | - |
dc.contributor.localId | A02904 | - |
dc.relation.journalcode | J01775 | - |
dc.identifier.eissn | 1538-9375 | - |
dc.identifier.pmid | 31080159 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S152586101930324X | - |
dc.subject.keyword | Aspiration pneumonia | - |
dc.subject.keyword | elderly | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | prognosis | - |
dc.subject.keyword | recurrent aspiration | - |
dc.contributor.alternativeName | Lee, Su Hwan | - |
dc.contributor.affiliatedAuthor | 이수환 | - |
dc.citation.volume | 20 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 1098 | - |
dc.citation.endPage | 1104.e4 | - |
dc.identifier.bibliographicCitation | JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, Vol.20(9) : 1098-1104.e4, 2019 | - |
dc.identifier.rimsid | 63837 | - |
dc.type.rims | ART | - |
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