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경동맥 조영증강 자기공명혈관조영술 때 경동맥 분지부에서 보이는 신호 불균질의 원인은 무엇인가?: 임상및 실험적 연구

Other Titles
 What is the Cause of Signal Inhomogeneity at the Carotid Bifurcation During Contrast Enhanced Carotid MRA?: In Vivo and in Vitro Studies 
 정기웅  ;  정태섭  ;  주진양 
 Journal of the Korean Radiologist Society (대한방사선의학회지), Vol.41(5) : 869-877, 1999 
Journal Title
 Journal of the Korean Radiologist Society (대한방사선의학회지) 
Issue Date
Carotid arteries, MR ; Carotid arteries, angiography ; Magnetic resonance (MR), contrast enhancement ; Magnetic resonance (MR), vascular studies
PURPOSE: To evaluate the hemodynamic causes of signal inhomogeneity at the carotid bulb that might be misinterpreted as pathologic signal defect in carotid contrast enhanced MRA(CEMRA). MATERIALS AND METHODS: Both carotid CEMRA and fast digital subtraction angiography(DSA) were conducted on 15 patients (28 carotid arteries) and arterial phase CEMRA images were compared with fast DSA images of the same patients. A 1.5T MR imager was used. The Turbo-FLASH sequence emplayed was TR/TE/FA= 3 .2m s / 1.3m s / 35 degree. For experimental study, we utilized handmade silicon phantoms of the tortuous carotid bifurcation; these might be expected to clearly demonstrate turbulent flow at the carotid bulb. In a closed circulatory system, both CEMRA and fast DSA involved the use of these phantoms. RESULTS: During CEMRA, inhomogeneous signals of varying degrees were found at the carotid bulb in 12/28 carotid arteries. When compared with sequential DSA images, incomplete mixing of contrast agent due to turbulent flow at the carotid bulb might be responsible for this inhomogeneity. This hypothesis was reinforced by successfully reproducing signal defects at the carotid bulb from the experimental CEMRA study using carotid phantoms that showed marked turbulent flow in the same area during DSA. CONCLUSION: Incomplete mixing of contrast agent caused by turbulent flow at the carotid bulb might be responsible for the signal inhomogeneity seen on carotid CEMRA.
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1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Chung, Tae Sub(정태섭)
Joo, Jin Yang(주진양)
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