We analyzed the PCDD/Fs and PCBs in human milk samples from a city and an industrial region by HRGC/HRMS. The average concentrations of PCDD/Fs and PCBs in human milk were 15.13 TEQpg/g fat and 5.64 TEQpg/g fat respectively. We discovered two kinds of homologue distributions. We compared congeners of each distributions with those of the commercial PCBs products. The daily intake of infant was predicted to be 60 TEQpg/㎏/day according to the mean concentration of PCDD/Fs based on primipara. This value is much higher than the estimated range for background exposure to adult in the USA (1-3 TEQpg/g fat).