여성 경도 알쯔하이머형 치매군, 치매의심군, 그리고 비치매 대조군간의 신경인지기능의 비교

Abstract

The objective of this study is to differentiate the mild dementia of Alzheimer type from the questionable dementia and non-demented elderly using the neurocognitive assessment. Subjects of 28 women who were registered to kwangju Community Mental Health Center were as follows：14 nondemented, 9 questionable dementia, 5 mild dementia of Alzheimer type. The diagnosis were made using DSM-Ⅳ, Clinical Dementia Rating Scale. The neurocognitive functions were assessed with following test tools 1) attention：Digit span, Visual span, Continuous attention；2) memory：Logical memroy, Verbal paired associates-easy/hard 3) visual perception and visuospatial ability：Visual recognition test, Construction；and 4) language：Comprehension and Aphasia severity rating scale；5) higher cortical function：Hypothesis formation, Perseveration, Similarity, Judgment, and Go-No-Go test. Group differences were analyzed with one way ANOVA test in SPSS 8.0 for win and LSD method as post-hoc analysis. The questionable dementia group showed significant difference in Verbal paired associateseasy pair, Construction, Aphasia severity rating scale and Similarity from the non-demented normal control group but showed no difference from the mildly demented group. These results suggest that the questionable dementia is actually very early or very mild stage of dementia of the Alzheimer type.