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위암에서 핵산 함량 양상과 휴지기 세포 분획의 예후인자로서의 의의

DC FieldValueLanguage
dc.contributor.author노성훈-
dc.contributor.author이강영-
dc.date.accessioned2019-11-11T05:55:33Z-
dc.date.available2019-11-11T05:55:33Z-
dc.date.issued2000-
dc.identifier.issn1226-0053-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/172263-
dc.description.abstractPurpose: DNA flow cytometry is a simple and easy method to assess the DNA content and the cell-cycle distribution of a tumor cell. The prognostic significance of the DNA content and the S-phase fraction in a gastric carcinoma has been controversial. The purpose of this study was to evaluate the prognostic significance of the nuclear DNA content and the S-phase fraction in patients with a gastric carcinoma. Methods: Between May 1995 and March 1996, 94 patients who were underwent a gastric resection for a gastric carcinoma were evaluated with DNA flow cytometry. Of them, 88 patients underwent a gastric resection with curative intent. The relationship of variable clinicopathological factors and of recurrence pattern to survival and nuclear DNA content were assessed. Results: The mean age was 55 years. 55 patients (58.5%) exbitied diploidy and 39 patients (41.5%) aneuploidy. There was no relationship between the clinicopathological factors and either the ploidy pattem or the S-phase fraction. Though the recurrence and its pattem were not different between the two ploidy group (p=0.860, 0.137), diploidy tended to recur locoregionally and aneuploidy hematogenously. Conclusion: The ploidy pattern was a significant prognostic factor in gastric carcinomas, but should be interpreted carefully.-
dc.description.statementOfResponsibilityopen-
dc.publisher대한외과학회-
dc.relation.isPartOfJOURNAL OF THE KOREAN SURGICAL SOCIETY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title위암에서 핵산 함량 양상과 휴지기 세포 분획의 예후인자로서의 의의-
dc.title.alternativePrognostic Significance of DNA Content and S-Phase Fraction in Gastric Carcinomas-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthor황수경-
dc.contributor.googleauthor이준호-
dc.contributor.googleauthor노성훈-
dc.contributor.googleauthor이강영-
dc.contributor.googleauthor최승호-
dc.contributor.googleauthor민진식-
dc.contributor.localIdA01281-
dc.contributor.localIdA02640-
dc.contributor.localIdA02640-
dc.relation.journalcodeJ01893-
dc.subject.keywordGASTRIC CARCINOMA-
dc.subject.keywordPrognosis-
dc.subject.keywordDNA flow cytometry-
dc.contributor.alternativeNameNoh, Sung Hoon-
dc.contributor.affiliatedAuthor노성훈-
dc.contributor.affiliatedAuthor이강영-
dc.contributor.affiliatedAuthor이강영-
dc.citation.volume59-
dc.citation.number5-
dc.citation.startPage602-
dc.citation.endPage608-
dc.identifier.bibliographicCitationJOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.59(5) : 602-608, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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