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공여자 신장무게와 공여자의 나이가 이식신 기능에 미치는 영향

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dc.contributor.author김유선-
dc.date.accessioned2019-11-11T05:55:21Z-
dc.date.available2019-11-11T05:55:21Z-
dc.date.issued2000-
dc.identifier.issn1226-0053-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/172261-
dc.description.abstractPURPOSE: We designed this study to identify the risk factors affecting the quality of graft after live donor kidney transplantation. METHODS: The study cohort included 259 adult patients who had been followed up for an average of 37 months after transplantation. Cyclosporine (CsA) and steroids were used as main immunosuppressive agents. Seven variables [HLA match, numbers of acute rejection (AR) within post-transplant 1 year, blood type compatibility, use of anti-lymphocyte antibody, age of donor (DA), age of recipient, and the donor kidney weight to recipient body weight ratio (KW/BW)] were examined by multiple regression analysis during the first 3 years. Serum creatinine (Scr), creatinine clearance rate (Ccr) and the 24 hours urinary excretion of protein (24 UP) were used as parameters. RESULTS: AR, DA, or KW/BW independently affected the quality of graft function. Scr, Ccr, or 24 UP at post-transplant 1 year was strongly correlated with AR (p<0.0001, p=0.002, or p=0.002, respectively). However, Scr, Ccr, or 24 UP at post-transplant 3 years was strongly affected by KW/BW (p<0.0001, p<0.0001, or p=0.008, respectively) or DA (p<0.0001, p=0.001, or p=0.039, respectively). CONCLUSION: Non-immunologic factors independently affected the graft function through the study periods. The impact of non-immunologic factors on the function of the graft increased year by year. During renal allocation, KW/BW and DA should be included as reference indices to improve the long-term graft function.-
dc.description.statementOfResponsibilityopen-
dc.publisher대한외과학회-
dc.relation.isPartOfJOURNAL OF THE KOREAN SURGICAL SOCIETY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title공여자 신장무게와 공여자의 나이가 이식신 기능에 미치는 영향-
dc.title.alternativeFactors Affecting the First 3-year Quality of Graft Function after Live Donor Kidney Transplantation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthor김명수-
dc.contributor.googleauthor김유선-
dc.contributor.googleauthor하헌주-
dc.contributor.googleauthor김혜진-
dc.contributor.googleauthor박제현-
dc.contributor.googleauthor박기일-
dc.contributor.localIdA00785-
dc.relation.journalcodeJ01893-
dc.subject.keywordLive kidney transplantation-
dc.subject.keywordNon-immunologic factors-
dc.subject.keywordDonor age-
dc.subject.keywordKidney weight-
dc.contributor.alternativeNameKim, Yu Seun-
dc.contributor.affiliatedAuthor김유선-
dc.citation.volume58-
dc.citation.number6-
dc.citation.startPage789-
dc.citation.endPage801-
dc.identifier.bibliographicCitationJOURNAL OF THE KOREAN SURGICAL SOCIETY , Vol.58(6) : 789-801, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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