352 349

Cited 0 times in

수두증 흰쥐 모델에서 수두증 정도에 따른 체성 감각 유발 장전위의 변화

DC Field Value Language
dc.contributor.author김동석-
dc.contributor.author박용구-
dc.contributor.author이배환-
dc.contributor.author최중언-
dc.date.accessioned2019-11-11T05:52:24Z-
dc.date.available2019-11-11T05:52:24Z-
dc.date.issued2000-
dc.identifier.issn1225-8245-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/172228-
dc.description.abstractObjective:Somatosensory evoked potential(SSEP) has been known to be a good method for evaluating brain stem function, but it is not sufficient to check the fine changes of cortical functions. A fine change of cortical function can be expressed with somatosensory evoked cortical field potential(SSEFP) rather than general SSEP. To confirm the usefulness of SSEFP for evaluating the cortical function, the authors simultaneously measured SSEFP and the intracranial pressure-volume index(PVI) in kaolin-induced hydrocephalic rats. Method:Hydrocephalus was induced with injection of 0.1ml kaolin-suspended solution into the cisterna magna in 60 Sprague-Dawley rats. The authors measured PVI and SSEFP 1 week after injection of kaolin-suspended solution. To evaluate the severity of induced hydrocephalus, we measured the transverse diameter of the lateral ventricle on the coronal slice of the rat brain 0.40mm posterior to the bregma. Result:The typical wave form of SSEFP in control rats showed a negative-positive complex wave at early latency. In SSEFP of normal rats, N0 is 10.0 msec, N1 15.3 msec, P1 31.2 msec and N1-P1 amplitude 15.4μV. As hydrocephalus progressed, the peak latency of N1 and P1 were delayed. In mild hydrocephalus, negative peak waves were split. The N1-P1 amplitude was decreased only in severe hydrocephalus. The changes of the characteristics of SSEFP according to the severity of hydrocephalus were well correlated with the changes of PVI. Shunting normalized the characteristics of SSEFP in relation to ventricular sizes and PVI in hydrocephalic rats. Conclusion:SSEFP may be useful for evaluating the impairment of cortical function in hydrocephalus.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한신경외과학회-
dc.relation.isPartOfJournal of Korean Neurosurgical Society (대한신경외과학회지)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title수두증 흰쥐 모델에서 수두증 정도에 따른 체성 감각 유발 장전위의 변화-
dc.title.alternativeChange of Somatosensory Evoked Field Potential according to the Severity of Hydrocephalus in Kaolin-induced Hydrocephalus of Rats-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Neurosurgery (신경외과학교실)-
dc.contributor.googleauthor김동석-
dc.contributor.googleauthor이광수-
dc.contributor.googleauthor박용구-
dc.contributor.googleauthor김세혁-
dc.contributor.googleauthor최중언-
dc.contributor.googleauthor이배환-
dc.contributor.googleauthor류재욱-
dc.contributor.googleauthorChun-Zhi Zhao-
dc.contributor.localIdA00402-
dc.contributor.localIdA01578-
dc.contributor.localIdA02791-
dc.contributor.localIdA04194-
dc.relation.journalcodeJ01521-
dc.subject.keywordKaolin-induced hydrocephalus-
dc.subject.keywordPressure-volume index-
dc.subject.keywordSomatosensory evoked potential-
dc.subject.keywordSomatosensory evoked cortical field potential.-
dc.contributor.alternativeNameKim, Dong Seok-
dc.contributor.affiliatedAuthor김동석-
dc.contributor.affiliatedAuthor박용구-
dc.contributor.affiliatedAuthor이배환-
dc.contributor.affiliatedAuthor최중언-
dc.citation.volume29-
dc.citation.number1-
dc.citation.startPage5-
dc.citation.endPage14-
dc.identifier.bibliographicCitationJournal of Korean Neurosurgical Society (대한신경외과학회지), Vol.29(1) : 5-14, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Physiology (생리학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.