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Helicobacter pylori 양성 소화성 궤양 환자에서 Omeprazole 제형에 따른 삼제요법의 비교

DC Field Value Language
dc.contributor.author이동기-
dc.date.accessioned2019-11-11T05:49:50Z-
dc.date.available2019-11-11T05:49:50Z-
dc.date.issued2000-
dc.identifier.issn1598-9992-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/172196-
dc.description.abstractBackground/Aims : We prospectively compared the efficacy and safety of the two products of omeprazole based triple therapy in patients with Helicobacter pylori (H. pylori)-positive active peptic ulcer. Methods : Seventy-four patients with endoscopically proven active peptic ulcer were divided into two groups: OAC-I group (n=37) which received the 6-weeks treatment of A product of omeprazole (20 mg, b.i.d.) plus 2 weeks treatment of amoxicillin (500 mg, b.i.d.) and clarithromycin (500 mg, b.i.d.); OAC-Ⅱ group (n=37) which received 6 weeks treatment of B product of omeprazole (20 mg, b.i.d.) plus 2 weeks treatment of the same antibiotics. The H. pylori and ulcer healing status were assessed at baseline and at the end of the 6-week therapy. Gastrointestnal symptoms, adverse events were checked and the standard laboratory examination was performed at each visit. Results : Eradication of H. pylori [intention to treat (n=77)/per protocol (n=66)] and healing rate of ulcer were 83.8%/ 96.9% and 93.8% in OAC-I group, 91.9%/100% and 97.1% in OAC-II group (P=0.477, P=0.608). No significant differences were found in symptom resolution, adverse events, and laboratory monitoring between the two groups. Conclusions : The two different products of omeprazole based triple therapy for ulcer showed similar healing rates and safety after 6-weeks treatment in patients with H. pylori-positive active peptic ulcer. (Kor J Gastroenterol 2000;36:29 - 38)-
dc.description.statementOfResponsibilityopen-
dc.languageKorean Journal of Gastroenterology-
dc.publisherKorean Journal of Gastroenterology-
dc.relation.isPartOfKorean Journal of Gastroenterology-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titleHelicobacter pylori 양성 소화성 궤양 환자에서 Omeprazole 제형에 따른 삼제요법의 비교-
dc.title.alternativeComparison of the Different Products of Omeprazole based Triple Therapy for Helicobacter pylori-Positive Peptic Ulcer Disease-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthor김현수-
dc.contributor.googleauthor이동기-
dc.contributor.googleauthor김광현-
dc.contributor.googleauthor정연수-
dc.contributor.googleauthor김재우-
dc.contributor.googleauthor서정인-
dc.contributor.googleauthor백순구-
dc.contributor.googleauthor권상옥-
dc.contributor.googleauthor조미연-
dc.contributor.localIdA02723-
dc.relation.journalcodeJ02015-
dc.identifier.eissn2233-6869-
dc.subject.keywordProducts of omeprazole-
dc.subject.keywordPeptic ulcer disease-
dc.contributor.alternativeNameLee, Dong Ki-
dc.contributor.affiliatedAuthor이동기-
dc.citation.volume36-
dc.citation.number1-
dc.citation.startPage29-
dc.citation.endPage38-
dc.identifier.bibliographicCitationKorean Journal of Gastroenterology, Vol.36(1) : 29-38, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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