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Helicobacter pylori 양성 소화성 궤양 환자에서 Omeprazole 제형에 따른 삼제요법의 비교
DC Field | Value | Language |
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dc.contributor.author | 이동기 | - |
dc.date.accessioned | 2019-11-11T05:49:50Z | - |
dc.date.available | 2019-11-11T05:49:50Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 1598-9992 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/172196 | - |
dc.description.abstract | Background/Aims : We prospectively compared the efficacy and safety of the two products of omeprazole based triple therapy in patients with Helicobacter pylori (H. pylori)-positive active peptic ulcer. Methods : Seventy-four patients with endoscopically proven active peptic ulcer were divided into two groups: OAC-I group (n=37) which received the 6-weeks treatment of A product of omeprazole (20 mg, b.i.d.) plus 2 weeks treatment of amoxicillin (500 mg, b.i.d.) and clarithromycin (500 mg, b.i.d.); OAC-Ⅱ group (n=37) which received 6 weeks treatment of B product of omeprazole (20 mg, b.i.d.) plus 2 weeks treatment of the same antibiotics. The H. pylori and ulcer healing status were assessed at baseline and at the end of the 6-week therapy. Gastrointestnal symptoms, adverse events were checked and the standard laboratory examination was performed at each visit. Results : Eradication of H. pylori [intention to treat (n=77)/per protocol (n=66)] and healing rate of ulcer were 83.8%/ 96.9% and 93.8% in OAC-I group, 91.9%/100% and 97.1% in OAC-II group (P=0.477, P=0.608). No significant differences were found in symptom resolution, adverse events, and laboratory monitoring between the two groups. Conclusions : The two different products of omeprazole based triple therapy for ulcer showed similar healing rates and safety after 6-weeks treatment in patients with H. pylori-positive active peptic ulcer. (Kor J Gastroenterol 2000;36:29 - 38) | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean Journal of Gastroenterology | - |
dc.publisher | Korean Journal of Gastroenterology | - |
dc.relation.isPartOf | Korean Journal of Gastroenterology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Helicobacter pylori 양성 소화성 궤양 환자에서 Omeprazole 제형에 따른 삼제요법의 비교 | - |
dc.title.alternative | Comparison of the Different Products of Omeprazole based Triple Therapy for Helicobacter pylori-Positive Peptic Ulcer Disease | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | 김현수 | - |
dc.contributor.googleauthor | 이동기 | - |
dc.contributor.googleauthor | 김광현 | - |
dc.contributor.googleauthor | 정연수 | - |
dc.contributor.googleauthor | 김재우 | - |
dc.contributor.googleauthor | 서정인 | - |
dc.contributor.googleauthor | 백순구 | - |
dc.contributor.googleauthor | 권상옥 | - |
dc.contributor.googleauthor | 조미연 | - |
dc.contributor.localId | A02723 | - |
dc.relation.journalcode | J02015 | - |
dc.identifier.eissn | 2233-6869 | - |
dc.subject.keyword | Products of omeprazole | - |
dc.subject.keyword | Peptic ulcer disease | - |
dc.contributor.alternativeName | Lee, Dong Ki | - |
dc.contributor.affiliatedAuthor | 이동기 | - |
dc.citation.volume | 36 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 29 | - |
dc.citation.endPage | 38 | - |
dc.identifier.bibliographicCitation | Korean Journal of Gastroenterology, Vol.36(1) : 29-38, 2000 | - |
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