발기부전과 조루증이 동반된 환자에서 Sildenafil(iagra)과 SS-cream의 병용효과

Abstract

Purpose: Premature ejaculation is the most common problem in patients with ejaculatory dysfunction and frequently occurs with erectile dysfunction. Although sildenafil (Viagra®) has dramatically improved the treatment of patients with erectile dysfunction, many still complain of premature ejaculation. We investigated the combined clinical efficacy of sildenafil and SS-cream in patients with erectile dysfunction and premature ejaculation.

Materials and Methods: Of men aged over 20 years who visited our Andrology clinic with erectile dysfunction, a total of 52 patients with concomitant premature ejaculation were enrolled. Each patient was administered with sildenafil for 4 weeks and then sildenafil plus SS-cream for 4 weeks. Sexual function was measured before and after therapy using an abbreviated version of the International Index of Erectile Function-5 (IIEF-5), which includes 5 categories regarding sexual function. Results: Mean score of IIEF-5 was 102±4.1 at baseline, 18.8±5.2 after treatment with sildenafil and 22.2±4.2 after treatment with sildenafil and SS-cream, respectively. Mean score of four domains of sexual function, that is, overall satisfaction, orgasmic function, erectile function, intercourse satisfaction was 1.8±0.4, 2.1±0.5, 3.8±0.9, 1.8±0.4 at baseline, 4.0±0.6, 3.6±0.6, 8.0±1.2, 3.4±0.6 after treatment with sildenafil, and 4.4±0.8, 4.2±0.6, 9,2±1.4, 4.4±0.8 after treatment with sildenafil and SS-cream, respectively. Patient satisfaction was significantly higher after sildenafil and SS-cream administration (90.4%) compared to sildenafil alone 80.8%.

Conclusion: The combination of sildenafil and SS-cream is more effective in patients with erectile dysfunction and premature ejaculation compared to sildenafil alone.