Cited 0 times in
급성 식도정맥류 출혈 환자에서 Somatostatin과 Vasopressin의 치료효과 비교: A Prospective Randomized Trial.
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김정호 | - |
dc.contributor.author | 백용한 | - |
dc.contributor.author | 이관식 | - |
dc.date.accessioned | 2019-11-11T05:34:39Z | - |
dc.date.available | 2019-11-11T05:34:39Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 1738-222X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171987 | - |
dc.description.abstract | Background/ A ims : Although endoscopic band ligation or injection sclerotherapy are the current standard therapies for bleeding esophageal varices, the best method for initial control is unclear . The aim of this prospective study was to compare the efficacy and toxicity of somatostatin and vasopressin in the management of esophageal variceal hemorrhage. Methods : From March, 1997 to September , 1998, 28 consecutive cirrhotic patients admitted to the Yon sei Medical Center because of active variceal bleeding were included in this trial. The patient s were randomized to receive either somatostatin (15 patient s) or vasopressin (13 patient s) for 48 hours. Results : There were nosignificant differences between the two treatment groups in relation to Child' s classification, amount of bleeding before randomization and unit s of blood transfu sed during therapy . Initial control of bleeding was achieved in 13 (86.7%) patient s receiving somatostatin and in 10 (76.9%) of those treated with vasopres sin. However , two patient s in the somatostatin group and two in the vasopressin group bled again during treatment . Therefore complete control of bleeding during the 48 hour s of therapy was achieved in 11 (73.4%) patient s treated with somatostatin and in eight (61.5%) of those receiving vasopressin. Differences were observed in complication s associated with each therapy. Vasopressin produced complications in four patient s (chest pain in two, hyperten sion in one and hyponatremia- induced seizure in one) while somatostatin produced minor complication in one patient. Conclusions : This study suggest s that somatostatin is efficaciou s in controlling acute hemorrhage from esophageal varices and has a lower risk of adver se effect s than vasopres sin.(Korean J Hepatol 2000 ;6 :468 - 473) | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English, Korean | - |
dc.publisher | Korean Association for the Study of the Liver | - |
dc.relation.isPartOf | Korean Journal of Hepatology (대한간학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | 급성 식도정맥류 출혈 환자에서 Somatostatin과 Vasopressin의 치료효과 비교: A Prospective Randomized Trial. | - |
dc.title.alternative | Comparison of Somatostatin and Vasopressin in the Control of Acute Esophageal Variceal Hemorrhage : A Prospective Randomized Trial | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Laboratory Medicine (진단검사의학교실) | - |
dc.contributor.googleauthor | 전재윤 | - |
dc.contributor.googleauthor | 정정일 | - |
dc.contributor.googleauthor | 백용한 | - |
dc.contributor.googleauthor | 이천균 | - |
dc.contributor.googleauthor | 최병현 | - |
dc.contributor.googleauthor | 이관식 | - |
dc.contributor.googleauthor | 문병수 | - |
dc.contributor.googleauthor | 한광협 | - |
dc.contributor.googleauthor | 문영명 | - |
dc.contributor.googleauthor | 김동기 | - |
dc.contributor.localId | A00903 | - |
dc.contributor.localId | A01829 | - |
dc.contributor.localId | A02666 | - |
dc.relation.journalcode | J02036 | - |
dc.identifier.eissn | 2093-8047 | - |
dc.subject.keyword | Somatostatin | - |
dc.subject.keyword | Vasopressin | - |
dc.subject.keyword | Esophageal variceal hemorrhage | - |
dc.contributor.alternativeName | Kim, Jeong Ho | - |
dc.contributor.affiliatedAuthor | 김정호 | - |
dc.contributor.affiliatedAuthor | 백용한 | - |
dc.contributor.affiliatedAuthor | 이관식 | - |
dc.citation.volume | 6 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 468 | - |
dc.citation.endPage | 473 | - |
dc.identifier.bibliographicCitation | Korean Journal of Hepatology (대한간학회지), Vol.6(4) : 468-473, 2000 | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.