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결핵성 흉막액 환자의 흉막액과 흉막 조직의 항산균 도말 및 결핵균 배양에 대한 전향적 연구

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dc.contributor.author김영삼-
dc.date.accessioned2019-11-11T05:32:21Z-
dc.date.available2019-11-11T05:32:21Z-
dc.date.issued2000-
dc.identifier.issn0368-6221-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171958-
dc.description.abstractBackground : Tuberculous pleural effusion is the most common extrapulmonary site of all disease due to Mycobacterium tuberculosis. The diagnosis of tuberculous pleural effusion is most often established by histologic examination of pleural biopsy specimens. This study documents the utility of smear and culture of pleural fluid and pleural biopsy specimens for tubercle bacilli. Methods : Between March 1998 and August 1999, we performed thoracentesis with or without pleural biopsies on 148 patients with pleural effusion according to protocol with Abrams needle. Before the pleural biopsy, a diagnostic thoracentesis was performed. Aliquots of pleural fluid (30 mL) were submitted for biochemical, cytologic, and bacteriologic studies, Ziehl- Neelsen staining and culture in Lowenstein-Jensen medium. At least five samples of parietal pleural tissue were obtained, one for mycobacterial study and another for histologic study. Results : Thirty-seven of the 148 patients were proved to have tuberculosis (24 men and 13 women) with a median age of 32 years (range, 21∼91). Pleural biopsy was performed on 35 of the 37 patients with tuberculous pleural effusion. Granuloma was present in 33 of the 35 patients investigated with acidfast bacilli in 9 patients. The smear for acid-fast bacilli of pleural fluid was positive in 1 patient and the culture for M. tuberculosis was positive in 5 of 37 patients. Pleural biopsy culture was positive in 3 of 35 patients. The 2 patients who could not carry out the pleural biopsy were positive in pleural fluid and pleural tissue mycobacterial culture, respectively. Conclusion : In our test, Ziehl-Neelsen staining and culture for M. tuberculosis of pleural fluid and pleural specimen gave a higher yield (5.4%) than the histologic methods alone in establishing the diagnosis of tuberculous pleural effusion. (Korean J Infect Dis 32:55∼59, 2000)-
dc.description.statementOfResponsibilityopen-
dc.languageKorean-
dc.publisher대한감염학회-
dc.relation.isPartOfKorean Journal of Infectious Diseases (감염)-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.title결핵성 흉막액 환자의 흉막액과 흉막 조직의 항산균 도말 및 결핵균 배양에 대한 전향적 연구-
dc.title.alternativeA Prospective Study of Ziehl-Neelsen Stain and Mycobacterial Culture of Pleural Fluid and Closed Pleural Biopsy Specimen in Tuberculous Pleural Effusion-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthor양동규-
dc.contributor.googleauthor김영삼-
dc.contributor.googleauthor이준구-
dc.contributor.googleauthor김성규-
dc.contributor.googleauthor이원영-
dc.contributor.localIdA00707-
dc.relation.journalcodeJ02040-
dc.subject.keywordTuberculous pleural effusion-
dc.subject.keywordPleural biopsy-
dc.subject.keywordZiehl-Neelsen stain-
dc.subject.keywordMycobacterial culture-
dc.contributor.alternativeNameKim, Young Sam-
dc.contributor.affiliatedAuthor김영삼-
dc.citation.volume32-
dc.citation.number1-
dc.citation.startPage55-
dc.citation.endPage59-
dc.identifier.bibliographicCitationKorean Journal of Infectious Diseases (감염), Vol.32(1) : 55-59, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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