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Uterine artery Doppler velocimetry in the prediction of adverse obstetric outcomes in unexplained MSAFP elevations

DC Field Value Language
dc.contributor.author박용원-
dc.date.accessioned2019-11-11T05:30:18Z-
dc.date.available2019-11-11T05:30:18Z-
dc.date.issued2000-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171930-
dc.description.abstractUnexplained maternal serum-fetoprotein (MSAFP) elevation has been known to be associated with adverse obstetric outcomes, however it is not sufficiently useful as a screening test. This study was undertaken to determine whether uterine artery Doppler velocimetry could define a subset of patients with an elevated MSAFP level in whom complications of pregnancy might develop. The subjects included 179 women between 26 and 28 weeks' gestation with MSAFP > or = 2.5 multiples of the median, in whom either the presence of an early diastolic notch or a resistance index 0.6 was considered as an abnormal Doppler velocimetry finding. Those subjects who displayed abnormal Doppler velocimetry findings showed an increased incidence of preeclampsia, preterm birth, IUGR, and IUFD compared to those subjects with only elevated MSAFP (p < 0.05). No differences were observed in the incidence of LBW. Positive predictive values of adverse obstetric outcomes were significantly higher in the group having both elevated MSAFP and abnormal Doppler velocimetry compared to the group with only elevated MSAFP (p < 0.05). Uterine artery Doppler velocimetry in the second trimester can improve the value of unexplained MSAFP elevation in the prediction of adverse obstetric outcomes.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHArteries/diagnostic imaging-
dc.subject.MESHFemale-
dc.subject.MESHForecasting-
dc.subject.MESHHumans-
dc.subject.MESHIncidence-
dc.subject.MESHPregnancy/blood*-
dc.subject.MESHPregnancy Complications*/epidemiology-
dc.subject.MESHUltrasonography-
dc.subject.MESHUterus/blood supply*-
dc.subject.MESHUterus/diagnostic imaging*-
dc.subject.MESHalpha-Fetoproteins/analysis*-
dc.titleUterine artery Doppler velocimetry in the prediction of adverse obstetric outcomes in unexplained MSAFP elevations-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Obstetrics and Gynecology (산부인과학교실)-
dc.contributor.googleauthorJae Eun Chung-
dc.contributor.googleauthorJae Sung Cho-
dc.contributor.googleauthorSung Shik Han-
dc.contributor.googleauthorYong Won Park-
dc.contributor.googleauthorJae Wook Kim-
dc.identifier.doi10.3349/ymj.2000.41.1.17-
dc.contributor.localIdA01581-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid10731914-
dc.subject.keywordUnexplained elevated maternal serum-fetoprotein-
dc.subject.keyworduterine artery Doppler Velocimetry-
dc.subject.keywordadverse pregnancy outcome-
dc.contributor.alternativeNamePark, Yong Won-
dc.contributor.affiliatedAuthor박용원-
dc.citation.volume41-
dc.citation.number1-
dc.citation.startPage17-
dc.citation.endPage21-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.41(1) : 17-21, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers

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