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Penile vibratory threshold changes with various doses of SS-cream in patients with primary premature ejaculation

DC Field Value Language
dc.contributor.author최영득-
dc.date.accessioned2019-11-11T05:26:44Z-
dc.date.available2019-11-11T05:26:44Z-
dc.date.issued2000-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171885-
dc.description.abstractSS-cream made with extracts from natural products is a topical agent for treating premature ejaculation (PE). In order to elucidate the penile vibratory threshold changes and clinical effects of various doses of SS-cream, 53 patients with primary PE were investigated in a double-blind randomized placebo-controlled study. The mean age was 37.3 +/- 6.4 years and mean ejaculatory latency was 1.37 +/- 0.52 minutes. Neither the patients nor their sexual partners were satisfied with their sexual lives. Vibratory threshold at the glans penis, penile shaft, scrotum and index finger were measured using a biothesiometer twice during the screening period and three times one hour after the application of respective creams (SS-cream 0.05, 0.10. 0.15, 0.20 gm and placebo 0.10 gm) on the glans penis according to the order of the allocation table in a randomized fashion. The efficacy of SS-cream was defined as when the vibration threshold increased by more than 4 microns compared to the value tested during the screening period. The vibratory thresholds at the glans penis increased significantly in a dose-dependent manner after the application of various doses (0.05, 0.10, 0.15, 0.20 gm) of SS-cream (p < 0.001), and the efficacy of SS-cream on the penile vibration threshold increased according to the increased dosage (penile shaft: 48.4, 51.6, 54.8, 64.5%, glans penis: 58.1, 67.7, 77.4, 83.9%, respectively). With these results, we concluded that SS-cream increased the penile sensory threshold dose dependently, and therefore it is clinically effective for treating the heightened penile sensory response in patients with PE.-
dc.description.statementOfResponsibilityopen-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYonsei Medical Journal-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHDouble-Blind Method-
dc.subject.MESHEjaculation/drug effects*-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHPenis/physiopathology*-
dc.subject.MESHPlant Extracts/therapeutic use*-
dc.subject.MESHPlants, Medicinal*-
dc.subject.MESHSensory Thresholds-
dc.subject.MESHSexual Dysfunction, Physiological/drug therapy*-
dc.subject.MESHSexual Dysfunction, Physiological/physiopathology*-
dc.subject.MESHTime Factors-
dc.subject.MESHVibration*-
dc.titlePenile vibratory threshold changes with various doses of SS-cream in patients with primary premature ejaculation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorZhong Cheng Xin-
dc.contributor.googleauthorYoung Deuk Choi-
dc.contributor.googleauthorWoong Hee Lee-
dc.contributor.googleauthorYeong Jin Choi-
dc.contributor.googleauthorWon Jae Yang-
dc.contributor.googleauthorHyung Ki Choi-
dc.contributor.googleauthorDong Kee Kim-
dc.identifier.doi10.3349/ymj.2000.41.1.29-
dc.contributor.localIdA04111-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid10731916-
dc.subject.keywordPremature ejaculation-
dc.subject.keywordvibration threshold-
dc.subject.keywordSS-cream-
dc.contributor.alternativeNameChoi, Young Deuk-
dc.contributor.affiliatedAuthor최영득-
dc.citation.volume41-
dc.citation.number1-
dc.citation.startPage29-
dc.citation.endPage33-
dc.identifier.bibliographicCitationYonsei Medical Journal, Vol.41(1) : 29-33, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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