Cited 21 times in
Penile vibratory threshold changes with various doses of SS-cream in patients with primary premature ejaculation
DC Field | Value | Language |
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dc.contributor.author | 최영득 | - |
dc.date.accessioned | 2019-11-11T05:26:44Z | - |
dc.date.available | 2019-11-11T05:26:44Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171885 | - |
dc.description.abstract | SS-cream made with extracts from natural products is a topical agent for treating premature ejaculation (PE). In order to elucidate the penile vibratory threshold changes and clinical effects of various doses of SS-cream, 53 patients with primary PE were investigated in a double-blind randomized placebo-controlled study. The mean age was 37.3 +/- 6.4 years and mean ejaculatory latency was 1.37 +/- 0.52 minutes. Neither the patients nor their sexual partners were satisfied with their sexual lives. Vibratory threshold at the glans penis, penile shaft, scrotum and index finger were measured using a biothesiometer twice during the screening period and three times one hour after the application of respective creams (SS-cream 0.05, 0.10. 0.15, 0.20 gm and placebo 0.10 gm) on the glans penis according to the order of the allocation table in a randomized fashion. The efficacy of SS-cream was defined as when the vibration threshold increased by more than 4 microns compared to the value tested during the screening period. The vibratory thresholds at the glans penis increased significantly in a dose-dependent manner after the application of various doses (0.05, 0.10, 0.15, 0.20 gm) of SS-cream (p < 0.001), and the efficacy of SS-cream on the penile vibration threshold increased according to the increased dosage (penile shaft: 48.4, 51.6, 54.8, 64.5%, glans penis: 58.1, 67.7, 77.4, 83.9%, respectively). With these results, we concluded that SS-cream increased the penile sensory threshold dose dependently, and therefore it is clinically effective for treating the heightened penile sensory response in patients with PE. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | Yonsei Medical Journal | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Double-Blind Method | - |
dc.subject.MESH | Ejaculation/drug effects* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Penis/physiopathology* | - |
dc.subject.MESH | Plant Extracts/therapeutic use* | - |
dc.subject.MESH | Plants, Medicinal* | - |
dc.subject.MESH | Sensory Thresholds | - |
dc.subject.MESH | Sexual Dysfunction, Physiological/drug therapy* | - |
dc.subject.MESH | Sexual Dysfunction, Physiological/physiopathology* | - |
dc.subject.MESH | Time Factors | - |
dc.subject.MESH | Vibration* | - |
dc.title | Penile vibratory threshold changes with various doses of SS-cream in patients with primary premature ejaculation | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Zhong Cheng Xin | - |
dc.contributor.googleauthor | Young Deuk Choi | - |
dc.contributor.googleauthor | Woong Hee Lee | - |
dc.contributor.googleauthor | Yeong Jin Choi | - |
dc.contributor.googleauthor | Won Jae Yang | - |
dc.contributor.googleauthor | Hyung Ki Choi | - |
dc.contributor.googleauthor | Dong Kee Kim | - |
dc.identifier.doi | 10.3349/ymj.2000.41.1.29 | - |
dc.contributor.localId | A04111 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 10731916 | - |
dc.subject.keyword | Premature ejaculation | - |
dc.subject.keyword | vibration threshold | - |
dc.subject.keyword | SS-cream | - |
dc.contributor.alternativeName | Choi, Young Deuk | - |
dc.contributor.affiliatedAuthor | 최영득 | - |
dc.citation.volume | 41 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 29 | - |
dc.citation.endPage | 33 | - |
dc.identifier.bibliographicCitation | Yonsei Medical Journal, Vol.41(1) : 29-33, 2000 | - |
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