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Perirolandicc hypoperfusion on single photon emission computed tomography in term infants with perinatal asphyxia

Authors
 C. S. Yoon  ;  Y. H. Ryu  ;  D. I. Kim  ;  C. I. Park  ;  S. Lee  ;  P. H. Yoon  ;  T. J. Jeon  ;  J. D. Lee 
Citation
 Neuroradiology, Vol.42(12) : 908-912, 2000 
Journal Title
 Neuroradiology 
ISSN
 0028-3940 
Issue Date
2000
MeSH
Asphyxia Neonatorum/complications ; Asphyxia Neonatorum/diagnostic imaging* ; Basal Ganglia/pathology ; Cerebellum/pathology ; Child, Preschool ; Cysteine/analogs & derivatives* ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Obstetric Labor Complications ; Organotechnetium Compounds ; Pregnancy ; Quadriplegia/diagnostic imaging* ; Quadriplegia/etiology ; Radiopharmaceuticals ; Thalamus/pathology ; Tomography, Emission-Computed, Single-Photon*
Keywords
Cerebral palsy ; Birth asphyxia ; Magnetic resonance imaging ; Single-photon emission computed tomography
Abstract
We describe the findings on single-photon emission computed tomography (SPECT) in patients with perinatal asphyxia at term, with perirolandic cortico-subcortical changes on MRI, and to correlate them with clinical features. SPECT of 7 patients was obtained after injection of 185–370 MBq of Tc-99m-ECD (ethyl cysteinate dimer). The patients had spastic quadriplegia (7/7) with perinatal asphyxia (6/7) at term (7/7). The results were correlated with the MRI findings. Hypoperfusion of the perirolandic cortex was clearly seen on SPECT in all patients, even in two with subtle changes on MRI. SPECT demonstrated a more extensive area of involvement than MRI, notably in the cerebellum (in 4), the thalamus (in 7) and basal ganglia (in 5), where MRI failed to show any abnormalities.
Full Text
https://link.springer.com/article/10.1007/s002340000357
DOI
10.1007/s002340000357
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Radiology (영상의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Dong Ik(김동익)
Lee, Jong Doo(이종두)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171818
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