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Comparison of tear secretion and tear film instability after photorefractive keratectomy and laser in situ keratomileusis(1).

 Jae Bum Lee  ;  Chang Hoon Ryu  ;  Jeong-Ho Kim  ;  Eung Kweon Kim  ;  Hong Bok Kim 
 Journal of Cataract and Refractive Surgery, Vol.26(9) : 1326-1331, 2000 
Journal Title
 Journal of Cataract and Refractive Surgery 
Issue Date
Adult ; Dry Eye Syndromes/physiopathology ; Dry Eye Syndromes/prevention & control ; Female ; Humans ; Keratomileusis, Laser In Situ* ; Lacrimal Apparatus/secretion* ; Lasers, Excimer ; Male ; Middle Aged ; Myopia/surgery ; Osmolar Concentration ; Photorefractive Keratectomy* ; Postoperative Period ; Prospective Studies ; Surface Tension ; Tears/secretion*
PURPOSE: To evaluate and compare tear secretion and tear film instability following photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK). SETTING: Department of Ophthalmology, Yonsei University School of Medicine, Seoul, Korea. METHODS: In a prospective study, 36 eyes (21 patients) had PRK and 39 eyes (25 patients) had LASIK to correct myopia. Tear secretion and tear film instability were tested preoperatively and 3 and 6 months postoperatively using Schirmer test values, tear breakup time (BUT) scores, and tear osmolarity. RESULTS: Six months after surgery, the change in Schirmer test values from preoperative levels was -14.57% +/- 6.39% (SD) in the PRK eyes and -23.40% +/- 5.94% in the LASIK eyes and the change in BUT scores, -12.54% +/- 8.28% and -18.79% +/- 13.01%, respectively. The change in tear osmolarity was 14.95% +/- 6.46% and 35.63% +/- 8.51%, respectively. CONCLUSIONS: The decrease in tear secretion was greater after LASIK than after PRK at 6 months. Proper treatment of dry eye is required after LASIK and PRK, particularly in the LASIK postoperative period.
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1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Eung Kweon(김응권) ORCID logo https://orcid.org/0000-0002-1453-8042
Kim, Jeong Ho(김정호) ORCID logo https://orcid.org/0000-0003-2479-0548
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